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Position: Home > Articles > Clinical Study of Lipo PGE1 in Treating Chronic Renal Failure Journal of Yangtze University(Natural Science Edition)Agricultural Science Volumn 2009,6 (3) 19-20+313

前列地尔治疗慢性肾衰竭20例临床观察

作  者:
姜鸿;程骏章;潘卉萱;朱晓华;胡艳芳
单  位:
长江大学临床医学院荆州市第一人民医院肾内科
关键词:
慢性肾衰竭;前列地尔注射剂;临床观察
摘  要:
目的:观察前列地尔注射剂治疗慢性肾衰竭患者4周后血肌酐(SCr)、血尿素氮(Bun)以及24h尿蛋白定量的变化。方法:将患者随机分为两组,治疗组给予前列地尔4周后,测定治疗前后血Cr、Bun以及24h尿蛋白定量的变化。对照组给予一般治疗。结果:治疗前后:①血Bun水平显著下降(P<0.05)。②血Cr水平显著下降(P<0.05)。③24h尿蛋白定量显著变化(P<0.01)。结论:前列地尔注射剂可进一步改善慢性肾衰竭患者的肾功能。
译  名:
Clinical Study of Lipo PGE1 in Treating Chronic Renal Failure
作  者:
Jiang Hong,Cheng Jun-zhang,Pan Hui-xuan,ZHU Xiao-hua,HU Yan-fang (Department of nephropathy,Clinic Medical School of Yangtze University,the First Hospital of Yangtze University,Jingzhou 434000,China)
关键词:
Chronic Renal Failure;Lipo PGE1;Clinical study
摘  要:
Objective:To observe the effect of the Lipo PGE1 on Chronic Renal Failure after one month in terms of serum creatinine(Scr),blood urea nitrogen(BUN) and 24h-urine protein excretion.Methods:All patients were randomly divided into two groups:treatment group and control group.The treatment group was given by venoclysis of the Lipo PGE1 for one month,serum creatinine,blood urea nitrogen and 24h-urine protein excretion were measured before and after treatment.The control group received general treatment.Results:①The level of blood urea nitrogen was significantly decreased after treatment(P <0.05);②The level of serum creatinine was significantly decreased(P <0.05);③There was a significant change in 24h-urine protein excretion(P <0.01).Conclusion:Lipo PGE1 is a safe drug in treatment of chronic renal failure.

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