中国农业科学院农业信息研究所 中国农学会
Agricultural Information Institute of CAAS China Association of Agricultural Science Societies
En
Ch
中国农业科学院农业信息研究所 中国农学会 主办

AI检索

订阅

返回顶部
当前位置: 首页 > 文章 > 奶牛乳房炎病原菌人工诱发奶山羊急性乳房炎试验 动物医学进展 2004,25 (4) 85-88
Position: Home > Articles > Inducing Acute Mastitis in Milk Goats by Using Three Common Pathogenic Bacteria Isolated from Dairy Mastitis Progress in Veterinary Medicine 2004,25 (4) 85-88

奶牛乳房炎病原菌人工诱发奶山羊急性乳房炎试验

作  者：
李宏胜;郁杰;李新圃;罗金印;徐继英;郭福存;张礼华
单  位：
中国农业科学院兰州畜牧与兽药研究所
关键词：
金黄色葡萄球菌;无乳链球菌;停乳链球菌;奶牛乳房炎;奶山羊
摘  要：
用从临床型乳房炎奶牛的乳样中分离的金黄色葡萄球菌、无乳链球菌、停乳链球菌 3种菌 ,经乳室注入不同的菌数感染泌乳奶山羊分别诱导急性乳房炎试验。结果表明 ,3种菌经奶山羊乳头注入均可引起程度不等的乳房炎症状 ,出现乳腺肿胀湿热、触之硬实或有痛感 ,乳汁颜色发生变化 ,奶中氯化物及细胞数均升高 ,产奶量下降 ,并伴有体温升高 ,心率增加等全身症状。这些病理变化的严重程度与攻菌菌株的毒力及攻菌量有一定的关系 ,其中以金黄色葡萄球菌攻菌后引起的乳房炎病理变化最为明显 ,无乳链球菌次之 ,停乳链球菌较轻。通过本试验初步测得了 3种菌人工感染奶山羊引起急性乳房炎的最小攻菌量 ,金黄色葡萄球菌为1 .52× 1 0 6个菌 ,无乳链球菌为 7.7× 1 0 6个菌 ,停乳链球菌为 3 .0× 1 0 5个菌 ,同时初步建立了人工感染泌乳奶山羊的乳房炎实验动物病理模型 ,为进一步研究乳房炎菌苗、病理学、抗菌药物药动学及药效学提供了实验基础
译  名：
Inducing Acute Mastitis in Milk Goats by Using Three Common Pathogenic Bacteria Isolated from Dairy Mastitis
作  者：
LI Hong-sheng,YU Jie,LI Xin-pu,LUO Jin-yin,XU Ji-ying,GUO Fu-cun,ZHANG Li-hua (Lanzhou Institute of Animal and Veterinary Pharmaceutics Science, CAAS,Lanzhou,Gansu,730050,China)
关键词：
S.aureus;S.agalactiae and S.dysgalactiae;dairy mastitis;milk goat
摘  要：
To induce acute mastitis in milk goats,the experiment was conducted by using three strains of bacteria (Staphylococcus aureus, Streptococcus agalactiae, and Streptococcus dysgalactiae) which were isolated from milk of dairy clinic mastitis.The results showed that injection of the three bacteria resulted in mastitis syndromes in different extent,such as mammary swelling, and hardening, solid and moist heat with painful feeling, changes of milk color, reduction of milk production, increased chloride and somatic cells, high body temperature, increased pulse and heart rate etc. The infection severity of mastitis in goats was closely related to virulence of bacteria and their dosages. Of three bacteria in milk goats, S. aureus can cause severe mastitis, next S. agalactiae. S. dysgalactiae cause only slight mastitis in milk goats. Generally, the syndromes of the disease appeared at 2 to 3 days post-infection and gradually declined and even disappeared completely. The minimum challenge dose of the three bacteria which cause acute mastitis in milk goats was: S. aureus, 1.52×10~6;S.agalactiae, 7.7×10~6 and S. dysgalactiae, 3.0×10~5. In order to study physiology and pathology of mastitis, antibacterial medicine, medicine dynamics and metabolism, we established the disease model in experimental animals that created better conditions for further study this disease.

相似文章

导出引用
计量
文章访问数: 5
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊

友情链接Friendly link
农业信息研究所Agricultural information institute 农业智能知识服务平台Agricultural intelligent knowledge service platform 农业学术服务平台Agricultural Knowledge Service System 中国知网CNKI 维普网VIP 万方WANFANG DATA
联系我们Contact us

电话Tell：010-82109652-808

邮箱E-mail：agrijournal@caas.cn

服务Service
关于我们About us 意见建议Opinions and suggest
版权说明Copyright
单位：中国农业科学院农业信息研究所 中国农学会 © 2017中国农业科学院农业信息研究所 ICP备案号：京ICP备09089781号-46