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Position: Home > Articles > The Progress of Natural Resistance Associated Macrophage Protein 1 Animal Husbandry and Feed Science 2011,32 (1) 34-36

NRAMP1基因的研究进展

作  者:
Guoqing Ca
单  位:
College of Animal Science and Veterinary Medicine,Shanxi Agricultural University,Taigu,030801 China
关键词:
correlation;natural resistance associated macrophage protein 1;characteristics;breeding application;disease;leishmani
摘  要:
天然抗性相关巨噬蛋白(natural resistance associated macrophage protein 1,NRAMP1)与多种胞内菌如结核分枝杆菌、沙门氏杆菌和利什曼原虫等易感和抗性相关。综述了NRAMP1基因的结构特点、作用机理、表达调控及其与疾病的相关性,以期为应用于猪的抗病育种提供理论依据。
译  名:
The Progress of Natural Resistance Associated Macrophage Protein 1
作  者:
XUE Shang-jun1,JIA Jing-min2,LIU Hong1,SHI Jia-zhong1,CAO Guo-qing2(1.Datong Pig Breeding Farm,Datong 037000,China;2.College of Animal Science and Veterinary Medicine,Shanxi Agricultural University,Taigu 030801,China)
关键词:
NRAMP1 gene;structure characteristics;mechanism;regulation and expression
摘  要:
Natural resistance associated macrophage protein 1 has been testified that it is correlation to resistance on a variety of intracellular bacteria such as Mycobacterium tuberculosis,Salmonella and Leishmania etc.In this paper,the structure characteristics of NRAMP1 gene,expression mechanism,regulation and correlation with disease was reviewed,it will provide the theoretical basis for breeding application in pig disease resistance.

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