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当前位置: 首页 > 文章 > 新型中兽药“黄金二白散”药效学研究 畜牧与饲料科学 2014,35 (4) 16-17
Position: Home > Articles > Pharmacodynamic Study on New Chinese Veterinary Drug “Huangjinerbai Powder” Animal Husbandry and Feed Science 2014,35 (4) 16-17

新型中兽药“黄金二白散”药效学研究

作  者：
L Zhan
单  位：
Shanxi Institute of Medicine and Life Scienc
关键词：
powder;huangjinerbai;test;dose;antibacterial test in vitro;metho
摘  要：
[目的]考察"黄金二白散"的抑菌及消炎作用。[方法]采用小鼠耳肿胀法和平板打孔法进行了"黄金二白散"的抗炎试验和体外抑菌试验。[结果]抗炎试验,小鼠耳平均肿胀度低剂量组为(1.25±0.78)mg,中剂量组为(0.51±0.38)mg,高剂量组为(0.42±0.35)mg,试验3组与空白对照组相比,差异极显著;体外抑菌试验,"黄金二白散"对金黄色葡萄球菌的抑菌值为21.7 mm,对痢疾杆菌的抑菌值为17.4 mm,对绿脓杆菌的抑菌值为14.6 mm,对大肠杆菌的抑菌值为16.4 mm,对变形杆菌的抑菌值为28.3 mm。[结论]"黄金二白散"具有一定的抗炎作用,对金黄色葡萄球菌、痢疾杆菌、绿脓杆菌、大肠杆菌、变形杆菌等细菌皆敏感,具有广谱抗菌作用,且与庆大霉素相比,抑菌效果更佳。
译  名：
Pharmacodynamic Study on New Chinese Veterinary Drug “Huangjinerbai Powder”
作  者：
ZHANG Lu;Shanxi Institute of Medicine and Life Science;
关键词：
Huangjinerbai Powder;;pharmacodynamics;;antibacterial anti-inflammatory
摘  要：
[Objective] The research aimed to study the antibacterial and anti-inflammatory effect of "Huangjinerbai Powder". [Method] The anti-inflammatory test and antibacterial test in vitro of "Huangjinerbai Powder" were carried out by using ear edema method of mice and disk diffusion method. [Result] The results of anti-inflammatory test showed that the average swelling degree of mice ear in low-dose group was(1.25±0.78) mg, and that in medium- dose group and high-dose group were(0.51± 0.38) and(0.42 ±0.35) mg. There was extremelt significant difference between test group 3 and control group. The results of antibacterial test in vitro showed that the bacteriostatic value of "Huangjinerbai Powder" on Staphylococcus aureus, Shigella castellani, Pseudomonas aeruginosa, Escherichia coli and Proteus vulgaris were 21.7, 17.4, 14.6, 16.4 and 28.3 mm respectively. [Conclusion] "Huangjinerbai Powder" had some anti-inflammatory effects, and it was sensitive to S. aureus, S. castellani, P. aeruginosa, E. coli and P. vulgaris and other bacteria. "Huangjinerbai Powder" had a broad spectrum of antibacterial activity. Compared with gentamicin, "Huangjinerbai Powder" had better antibacterial effects.

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