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Position: Home > Articles > Research Progress of FeIFN-ω Chinese Journal of Veterinary Drug 2018 (12) 69-74

猫ω干扰素研究进展

作  者:
孙明洁;董国英;张雪竹;胡桂学
单  位:
吉林农业大学动物科学技术学院;北京师范大学全球变化与地球系统科学研究院
关键词:
猫ω干扰素;抗病毒活性;作用机制;临床应用
摘  要:
猫ω干扰素因其较高的抗病毒、抗增殖和抗肿瘤效果以及免疫调节作用引起广泛关注与研究。结合ω干扰素相关研究结果,综述猫ω干扰素的结构特征、生物学活性以及抗病毒的作用机制,综合分析其在临床上对FCV、FHV-1、FIV、FCGS及FIP等几种常见猫病毒病的治疗效果,以期为临床上寻求新型有效的动物抗病毒药物提供参考。
译  名:
Research Progress of FeIFN-ω
作  者:
SUN Ming-jie;DONG Guo-ying;ZHANG Xue-zhu;HU Gui-xue;College of Animal Science and Technology,Jilin Agricultural University;Global Change and Earth System Academy,Beijing Normal University;
单  位:
SUN Ming-jie%DONG Guo-ying%ZHANG Xue-zhu%HU Gui-xue%College of Animal Science and Technology,Jilin Agricultural University%Global Change and Earth System Academy,Beijing Normal University
关键词:
FeIFN-ω;;antiviral activity;;mechanism;;clinical research
摘  要:
With the developing of the research on FeIFN-ω,its high antiviral,antiproliferative and antitumor effects,as well as immune regulation,has attracted widespread attention and research. Based on the related research results of IFN-ω,the structure,biological activity and antiviral mechanism of FeIFN-ω were reviewed in the paper. The therapeutic effects of FeIFN-ω on several common feline viral diseases,such as FCV,FHV-1,FIV,FCGS and FIP,were analyzed comprehensively in order to seek new and effective animal antiviral drugs in clinic.

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