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Position: Home > Articles > Effects of PCBs on acute toxication and oxdative stress in Boleophthalmus pectinirostris Hebei Fisheries 2010 (6) 1-3+36

多氯联苯对大弹涂鱼的急性毒性以及氧化应激

作  者:
孙梦蝶;马满华;张倩;蔡怡博;金圣朝;何闪英
单  位:
浙江工商大学环境科学与工程学院
关键词:
PCBs;Aroclor1248;大弹涂鱼
摘  要:
测定Aroclor 1248对大弹涂鱼96 h的半数致死浓度(LC50);进而以浓度为10和100μg/L的Aroclor1248溶液对大弹涂鱼经口染毒28 d,测定其总SOD、CAT、GPx、活性以及脂质过氧化产物丙二醛(MDA)含量。结果表明Aroclor1248对大弹涂鱼的96 h LC50为295.15μg/L。暴露于10μg/L Aroclor 1248 28 d的大弹涂鱼SOD活性明显大于空白和100μg/L剂量组(p<0.05),添加Aroclor 1248的实验组中CAT活性均高于对照组,100μg/L Aroclor 1248强度下GPx活性明显高于其他三组(p<0.05),10μg/L Aroclor 1248强度下GPx活性略高于对照组。100μg/L Aroclor 1248强度中MDA明显高于其他三组(p<0.05),表明Aroclor1248对大弹涂鱼抗氧化和脂质过氧化系统有明显干扰作用。
译  名:
Effects of PCBs on acute toxication and oxdative stress in Boleophthalmus pectinirostris
作  者:
Sun Mengdie,Ma Manhua,Zhang Qian,CaiYibo,Jin Shengchao,He Shanying*(The College of Environmental Science and Engineering,Zhejiang Gongshang University,Zhejiang Hangzhou 310012)
关键词:
PCBs;Aroclor 1248;Boleophthalmus pectinirostris
摘  要:
The 96 h LC50 of Aroclor 1248 for Boleophthalmus pectinirostris was determined,and then B.pectinirostris were exposed orally to 10 and 100 μg/L of Aroclor 1248 solution for 28 d,and the total SOD,CAT and GPx activity and the lipid peroxidation product malondialdehyde(MDA) content were measured.Results showed the to 96 h LC50 of Aroclor1248 for B.pectinirostris was 295.15 μg/L.SOD activity exposed to 10 μg/L Aroclor 1248 was greater than the controls and 100 μg/L treatment(p<0.05).CAT activity of the Aroclor 1248 treatment is without exception higher than the controls.GPx activity and MDA content of 100 μg/L treatment were higher than the other three groups(p<0.05),and the GPx activity of 10 μg/L treatment was a little higher than the controls.Those indicated that Aroclor 1254 could obviously disturb the antioxidation and lipid peroxidation system of B.-pectinirostris.

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