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Position: Home > Articles > Progress on Ghrelin in Ruminants Progress in Veterinary Medicine 2013,34 (6) 149-153

反刍动物Ghrelin研究进展

作  者:
刘璐;夏利宁;姚刚;赵红琼
单  位:
新疆农业大学动物医学学院
关键词:
Ghrelin;反刍动物;内分泌;生长激素;食欲
摘  要:
Ghrelin是生长激素促泌素受体至今发现的唯一内源性配体,主要分泌于胃的脑肠肽,具有促进生长激素释放和调节食欲等广泛生物学作用。目前对于Ghrelin的研究主要集中在鼠类和人类,而关于反刍动物的研究相对较少,深度也不够。论文概述了Ghrelin及其受体的发现和反刍动物Ghrelin的组织分布;从Ghrelin对生长激素分泌的影响,促进食欲、调节能量平衡,调控生殖等方面阐述了Ghrelin对反刍动物的生物学作用,从摄食和内分泌等因素探讨了反刍动物Ghrelin分泌的调节,以期为进一步开展反刍动物Ghrelin及其受体的研究提供参考。
译  名:
Progress on Ghrelin in Ruminants
作  者:
LIU Lu,XIA Li-ning,YAO Gang,ZHAO Hong-qiong(College of Veterinary Medicine,Xinjiang Agricultural University,Urumqi,Xinjiang,830052,China)
关键词:
Ghrelin;ruminant;endocrine;growth hormone;appetite
摘  要:
So far,ghrelin is the only endogenous ligand of growth hormone secretagogue receptors,mainly secreted from the stomach.Ghrelin was found with a wide range of biological effects: stimulation the release of growth hormone,regulation of appetite and so on.Studies on ghrelin were mostly focused on the rodent and human,and a few in ruminants.This article summarized the discovery of ghrelin and its receptors;the tissue distribution of ghrelin in ruminants;the biological functions of ghrelin,including the effect on growth hormone secretion,promoting appetite,regulating energy balance and reproduction;the regulation of ghrelin by feeding and endocrine in ruminants.

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