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甘薯叶柄藤多糖的免疫调节作用研究

作  者:
高荫榆;罗丽萍;洪雪娥;夏冬华;陈才水
单  位:
南昌大学食品科学教育部重点实验室
关键词:
甘薯叶柄藤;多糖;免疫调节作用;非特异性免疫;特异性体液免疫;PSPV
摘  要:
研究薯蔓多糖(PSPV)对动物的非特异性免疫和特异性体液免疫调节作用。采用碳粒廓清实验研究PSPV对正常和免疫低下小鼠的非特异性免疫功能;血清溶血素测定法研究PSPV的特异性体液免疫功能。结果表明:PSPV可提高正常和免疫低下小鼠的廓清指数K和呑噬指数α,800mg/kg剂量的PSPV可显著提高小鼠血清的血清溶血素HC50。结论:PSPV具有促进单核巨噬细胞系统吞噬功能的作用,可增强小鼠的非特异性免疫功能,同时也可极显著地增强小鼠的特异性体液免疫功能。
译  名:
Study on Immunoregulation Effect of Polysaccharides from Sweet Potato Vines in Mice
作  者:
GAO Yin-yu,LUO Li-ping,HONG Xue-e,XIA Dong-hua,CHEN Cai-shui (Key Laboratory of Food Science, Ministry of Education, Nanchang University, Nanchang 330047,China)
关键词:
sweet potato leaf,stalk and stem;polysaccharides;immunoregulation;non-specific immunity; humoral immunity;PSPV(poly saccharides from sweef potato vines)
摘  要:
Purpose: To investigate the immunoregulation effect of polysaccharides from sweet potato vines (PSPV). Methods: By using carbon particle clearance test, study the nonspecific immunological function of (PSPV) on normal and immunosuppression mice. By using the hemolysin test, study the specific humoral immunological effect of PSPV on normal mice. Results: The carbon particle clearance index and phagocytic index of normal and immunosuppression mice are increased by giving PSPV to the mice. HPSPV, 800mg/kg dose, has remarkably significant effect on HC50. Conclusions: PSPV has potent enhancement effects on non-specific and specific humoral immunity function of mice.

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