摘 要：
2 0 0只商品代肉鸡分成低温处理组和对照组 ,处理组在 1 5日龄利用 1 5～ 1 8℃低温诱发肉鸡肺动脉高压和腹水症。用放射免疫诊断盒测定处理后 1 9、2 7、33、40日龄血浆、肺脏 TXB2 和 6 -酮 - PGF1α的动态变化 ,利用SMUP- 2 A生物信号处理系统监测肺动脉压变化。结果表明肺脏和血浆 TXB2 在低温早期均出现升高 ,肺动脉低压组、高压组也出现显著性升高 ;低温处理早期血浆和肺脏组织6 -酮 - PGF1α浓度呈显著性降低 ,肺动脉高压组、低压组与对照组相比 ,明显降低。低温处理 2周后肺动脉出现高压 ,这提示低温早期TXB2 /PGI2 失去平衡 ,肺脏和血液中 TXB2 升高可能是造成低温早期肺血管收缩、肺动脉高压的主要因素之一
译 名：
Influence of Thromboxane and Prostacyclin on Broiler High Pulmonary Artery Pressure
作 者：
HE Cheng,ZHAO De ming,LIANG Li cheng,XIA Guo liang (Veterinary Medicine College,China Agriculture University,Beijing 100094,China)
关键词：
thromboxane;prostacyclin;high pulmonary arterry pressure; broilers
摘 要：
Two hundred broilers were divided into treated group and control group.The half of broilers were reared in 15～18 ℃ to induce high pulmonary artery pressure on day 15.The concentration of thromboxane B(TXB 2) and prostacyclin(PGI 2) was analysed using radiation immunization diagnosis box.The Biological information System of SMUP 2A was used to measure pulmonary artery pressure.The experiment shows that TXB 2 of lung and plasma increases in early cold time,the same results occur in high pulmonary artery pressure and low pulmonary artery pressure group.6 keto PGF 1α in lung and plasma decreased significantly as compared with control group.The concentration of 6 keto PGF 1α decrease in high pressure group and low high pressure group.The broiler high pulmonary artery pressure developed on second week after exposed to cold stress.All these evidence imply imbalance of TXB 2 and PGI 2 in early cold time.Increasing thromboxane might contribute to lung artery contract and elevation of pulmonary artery pressure.
