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Position: Home > Articles > The dual antimicrobial and immunomodulatory roles of host defense peptides and their applications in animal production Journal of Animal Science and Biotechnology 2022,13 (1)

The dual antimicrobial and immunomodulatory roles of host defense peptides and their applications in animal production

作者：

Di Wu;Linglong Fu;Weizhang Wen;Na Don

单位：

State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, Chin;State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, China;State Key Laboratory of Animal Nutrition, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China.

关键词：

Antimicrobials;Host defense peptides;Immunomodulation;Poultry;Ruminants;Swin

摘要：

Host defense peptides (HDPs) are small molecules with broad-spectrum antimicrobial activities against infectious bacteria, viruses, and fungi. Increasing evidence suggests that HDPs can also indirectly protect hosts by modulating their immune responses. Due to these dual roles, HDPs have been considered one of the most promising antibiotic substitutes to improve growth performance, intestinal health, and immunity in farm animals. This review describes the antimicrobial and immunomodulatory roles of host defense peptides and their recent applications in animal production.

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The dual antimicrobial and immunomodulatory roles of host defense peptides and their applications in animal production

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