Position: Home > Articles > Effects of Medium Components on Taxol Production of Nodulisporium sylviforme
Journal of Fungal Research
2003
(1)
24-27
培养基组成对树状多节孢(Nodulisporium sylviforme)紫杉醇产量的影响
作 者：
赵凯;周东坡;王伟
单 位：
黑龙江大学生命科学学院
关键词：
树状多节孢;紫杉醇产生菌;微生物发酵;紫杉醇;前体
摘 要：
采用正交试验法 ,研究了醋酸钠、苯丙氨酸、酪氨酸、亮氨酸对紫杉醇产生菌HQD3 3 产生紫杉醇的影响。结果表明 ,它们之间的协同作用对提高紫杉醇产量有显著影响。在改良的S - 7培养基基础上 ,再加入醋酸钠 1 0g/L、苯丙氨酸 5 0mg/L、酪氨酸 1 5mg/L、亮氨酸 6 0mg/L ,可以使紫杉醇产生菌HQD3 3 产生紫杉醇产量提高到 2 0 3 6 5 6 μg/L。
译 名：
Effects of Medium Components on Taxol Production of Nodulisporium sylviforme
作 者：
ZHAO Kai 1,2 , ZHOU Dong po 1, WANG Wei 1 1 Life and Science College, Heilongjiang University,Harbin, Heilongjiang 150080, China 2 Food and Science Institute, Northeast Agricultural University,Harbin, Heilongjiang 150030,China
关键词：
Nodulisporium sylviforme ;HQD 33 ; microbiological fermentation; taxol; precursor
摘 要：
The effects of the components of media on taxol producing strain Nodulisporium sylviforme were studied in the experiment by using orthogonal experiment The results showed that their interactions dramatically promoted taxol biosynethesis On the basic of the primary S 7, the addition of 1 0 mg/L acetate, 5 0 mg/L phenylalanine, 1 5 mg/L tyrosine and 6 0 mg/L leucine into the media dramatically increased taxol yield to 203 65 μg/L
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