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Position: Home > Articles > Progress of Cyclin-dependent Kinase(CDK5) Journal of Animal Science and Veterinary Medicine 2010,29 (6) 47-49

细胞周期素依赖蛋白激酶5(CDK5)研究进展

作  者:
范瑞文;张俊珍;刘佳;董常生
单  位:
山西农业大学动物科技学院
关键词:
CDK5;细胞分化;细胞凋亡;磷酸化
摘  要:
CDK5属于细胞周期素依赖性蛋白激酶(CDK)家族成员,在多种组织中表达,可对细胞的分化和凋亡起作用,也可以通过磷酸化不同的底物发挥多种生物学作用。本文就其特性和功能进行了综述。
译  名:
Progress of Cyclin-dependent Kinase(CDK5)
作  者:
FAN Rui-wen,ZHANG Jun-zhen,LIU Jia,DONG Cang-sheng(College of Animal Science and Technology,Shanxi Agricultural University,Taigu Shaanxi 030801,China)
关键词:
CDK5;cell differentiation;cell apoptosis;phosphorylation
摘  要:
CDK5 is one of the members of cyclin-dependent kinase(CDK) family,which is expressed in many tissues.CDK5 can play a role in cell differentiation and apoptosis.CDK5 can also play a variety of different biological effects on the substrate by phosphorylation.In this paper,the characteristics and functions of CDK5 were overviewed.

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