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Position: Home > Articles > Effects of Specificity Anesthetic for Deer on Na~+-K~+-ATPase Activity in Cerebral Cortex of Rats Hubei Agricultural Sciences 2016,55 (4) 964-965+970

鹿特异性复合麻醉剂对大鼠大脑皮层Na~+-K~+-ATP酶活性的影响

作者：

冯雪;付连军;林博;常乃元;李京乘;李闻轩;尹柏双

单位：

吉林农业科技学院动物科技学院

关键词：

鹿特异性复合麻醉剂;大鼠;大脑皮层;Na+-K+-ATP酶

摘要：

通过测定鹿特异性复合麻醉剂麻醉下大鼠大脑皮层Na~+-K~+-ATP酶活性的变化,探讨了其麻醉与大鼠大脑皮层Na~+-K~+-ATP酶的关系。将32只纯种SD大鼠随机分成对照组、诱导组、麻醉组和催醒组,对照组大鼠按30 m L/kg体重腹腔注射生理盐水,其余各组按30 mg/kg体重腹腔注射鹿特异性复合麻醉剂,于各时间点冰上采集各组大鼠大脑皮层,采用比色法测定其Na~+-K~+-ATP酶活性。结果显示,药物作用后大鼠大脑皮层Na~+-K~+-ATP酶活性显著低于对照组(P<0.05或P<0.01)。该结果提示大鼠大脑皮层Na~+-K~+-ATP酶活性变化与鹿特异性复合麻醉剂的麻醉作用具有相关性。

译名：

Effects of Specificity Anesthetic for Deer on Na~+-K~+-ATPase Activity in Cerebral Cortex of Rats

作者：

FENG Xue;FU Lian-jun;LIN Bo;CHANG Nai-yuan;LI Jing-cheng;LI Wen-xuan;YIN Bai-shuang;Department of Animal Medicine,Jilin Agricultural Science and Technology;

关键词：

specificity anesthetic for deer;;rats;;cerebral cortex;;Na+-K+-ATPase

摘要：

This experiment was aimed to determine the activity of Na~+-K~+-ATPase in rats' cerebral cortex region and investigate the relationship between specificity anesthetic for deer and Na~+-K~+-ATPase in cerebral cortex. 32 SD rats were randomly divided into control group, induction group, anesthesia group and the wake group. Rats of the control were injected with saline(30 m L / kg),rats of the other group were injected with drug(30 mg / kg). The samples of cerebral cortex in different period were separated and the activities of Na~+-K~+-ATPase were determined by using colorimetry methods. The results showed that the activities of Na~+-K~+-ATPase in cerebral cortex after administration were decreased obviously compared with that in the control group(P<0.05 or P<0.01). It indicated that the changes of the activity of Na~+-K~+-ATPase in the cerebral cortex were correlated with the specificity anesthetic for deer.

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鹿特异性复合麻醉剂对大鼠大脑皮层Na~+-K~+-ATP酶活性的影响

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