当前位置: 首页 > 文章 > Kisspeptins/GPR54系统及其在动物性发育中的作用 中国畜牧兽医 2009 (12) 95-99
Position: Home > Articles > Kisspeptins/GPR54 System and Puberty Onset China Animal Husbandry & Veterinary Medicine 2009 (12) 95-99

Kisspeptins/GPR54系统及其在动物性发育中的作用

作  者:
张营;郁建锋;顾志良
单  位:
常熟理工学院生物与食品工程学院;常熟理工学院生物系
关键词:
GnRH;下丘脑—垂体—性腺轴;kisspeptins/GPR54系统;信号通路
摘  要:
促性腺释放激素(gonadotropin-releasing hormone,GnRH)脉冲式释放的激活是动物性发育的关键。研究结果发现,kisspeptins/GPR54系统对GnRH脉冲式释放的激活起到了重要作用,是性发育启动的调节器。在kisspeptins/GPR54胞内信号通路方面的研究也已经证实,kisspeptins能通过GPR54受体激活多种信号,以发挥其它功能。另外,光周期、机体能量储备等也是影响动物性发育的重要因素。
译  名:
Kisspeptins/GPR54 System and Puberty Onset
作  者:
ZHANG Ying1,2,YU Jian-feng1,GU Zhi-liang1(1.Department of Life Science and Technology,Changshu Institute of Technology,Changshu 215500,China;2.College of Preclinical Medicine and Biological Science,Soochow University,Suzhou 215123,China)
关键词:
GnRH;HPG;kisspeptins/GPR54 system;signaling pathway
摘  要:
The activation of GnRH pulsatile release is a key step of animal sexual development.Studies show that kisspeptins/GPR54 system,playing a pivotal role in activation of GnRH pulsatile release,is a regulator of sexual development onset.Studies regarding the intracellular signaling pathways on kisspeptins/GPR54 confirm that kisspeptins can activate a wide variety of signals via GPR54 to exert the other roles.Additionally,some factors such as photoperiod and energy reserve affect animal sexual development remarkably.

相似文章

计量
文章访问数: 14
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊