Position: Home > Articles > Virulence Measure of α-chlorohydrin and Bromadiolone to Ochotona curzoniae and Observation of the α-chlorohydrin's Influence to Testis
Journal of Sichuan Forestry Science and Technology
2009,30
(5)
88-91
α-氯代醇和溴敌隆对黑唇鼠兔的毒力测定和睾丸病理观察
作 者：
吴宥析;刘少英;钟妮娜;赵杰;孙志宇
单 位：
四川农业大学动物医学院;四川省林业科学研究院
关键词：
α-氯代醇;溴敌隆;黑唇鼠兔LD50;睾丸;病理
摘 要：
LD50是毒饵浓度配制的关键数据。为了在黑唇鼠兔防治工作中准确掌握α-氯代醇和溴敌隆毒饵浓度,测定了α-氯代醇和溴敌隆毒对黑唇鼠兔的LD50并观察了α-氯代醇对睾丸的影响。通过用改良寇氏法计算急性口服致死中量结果,石蜡切片HE染色。α-氯代醇和溴敌隆对黑唇鼠兔的急性口服致死中量(LD50)分别为103.1644 mg.kg-1和88.7799 mg.kg-1;病理组织学观察可见睾丸组织出现明显的病理学改变。结果表明,按GB15670-1995灭鼠药毒力分级标准,这两种灭鼠剂对黑唇鼠兔为中等毒性。
译 名：
Virulence Measure of α-chlorohydrin and Bromadiolone to Ochotona curzoniae and Observation of the α-chlorohydrin's Influence to Testis
作 者：
WU You-xi1 LIU Shao-ying2 ZHONG Ni-na1* ZHAO Jie2 SUN Zhi-yu2(1.College of Veterinary Medicine,Sichuan Agricultural University,Ya'an 625014,China;2.Sichuan Academy of Forestry,Chengdu 610018,China)
关键词：
α-chlorohydrin,Bromadiolone,Ochotona curzoniae,LD50,Testis,Pathology
摘 要：
Objective Research α-chlorohydrin's and Bromadiolone's virulence to Ochotona curzoniae and observe the α-chlorohydrin's influence to testis.Methods Divide the test Ochotona curzoniae into groups randomly,pour the stomach,and calculate the LD50 results by Karber's method;paraffin imbedding,hematoxylin and eosin stain.Results α-chlorohydrin's and Bromadiolone's virulence to Ochotona curzoniae(LD50) are 103.1644 mg·kg-1 and 88.7799 mg·kg-1.It could be seen that the testis has a significant histological change by the pathologic histological observation.Conclusion These two rodenticides to Ochotona curzoniae are middle virulence by virulence grading standard on GB15670-1995.
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