中国农业期刊集成服务平台

当前位置: 首页 > 文章 > 三氟氯氰菊酯对小鼠肝、肾的影响农药 2011,50 (10) 48-49+58

Position: Home > Articles > Liver and Kidney of Toxic Effects Induced by Lambdacyhalothrin in Mice Agrochemicals 2011,50 (10) 48-49+58

三氟氯氰菊酯对小鼠肝、肾的影响

作者：

沈明浩;李玖营;权伍荣

单位：

吉林农业大学食品科学与工程学院;延边大学农学院

关键词：

三氟氯氰菊酯;蓄积毒性;病理;生化指标

摘要：

[目的]以三氟氯氰菊酯对小鼠的蓄积毒性试验为基础,通过观察三氟氯氰菊酯染毒对肝、肾组织病理学改变及肝组织生化指标等的影响来评价其对小鼠肝、肾的毒性。[方法]肝、肾组织经固定液固定后,常规脱水,石蜡包埋,切片,染色,光镜下观察病理改变。检测肝组织生化指标:酸性磷酸酶(ACP)、碱性磷酸酶(AKP)、乳酸脱氢酶(LDH)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-PX)活性测定。以上酶指标均采用南京建成生物工程研究所试剂盒所提供的方法测定。[结果]蓄积毒性试验组中,肝脏切片有崩解现象,为局灶性坏死,其余肝部位无异常;肾脏切片为局灶性坏死程度严重,此种病变多见于肾皮质细胞,髓质细胞无异样变化。试验组小鼠体质量与对照组相比增重减少,且有极显著差异(P<0.01)。AKP无显著差异(P>0.05),ACP、LDH、SOD存在显著差异(0.01

译名：

Liver and Kidney of Toxic Effects Induced by Lambdacyhalothrin in Mice

作者：

SHEN Ming-hao1,LI Jiu-ying1,QUAN Wu-rong2(1.College of Food Science and Engineering,Jilin Agricultural University,Changchun 130118,China;2.Agricultural College,Yanbian University,Yanji 133002,Jilin,China)

关键词：

lambdac alothrin;accumulation toxicity;pathology;biochemical indicators

摘要：

[Aims] Based on the accumulation toxicity of lambdac alothrin in mice,it was to evaluate the impact of liver and kidney in mice by observing the pathology change of liver and kidney,biochemical indicators of liver tissue.[Methods] The liver and kidney was fixed by the fixative followed by the conventional dehydration,embedded in paraffin,sectioned and stained,the pathological changes was observed under light microscope.Biochemical indicators of liver tissue: The activities of ACP,AKP,LDH,SOD and GSH-PX were measured respectively with testing kits provided by Nanjing Jiancheng Bioengineering Institute.[Results] The accumulation toxic of experimental group,liver biopsy have disintegration phenomenon,for the focal necrosis,and the remaining parts of the liver without abnormalities;Focal necrosis of the kidney biopsy was serious,this disease extent in renal cortical cells,medulla cells without peculiar change.Compared with the control group,the weight increment of mice reduced,and there was significant difference(P <0.01).AKP had no significant difference(P>0.05),while ACP,LDH,SOD had significant difference(0.01

相似文章

华北棉区棉铃虫对三种杀虫剂的抗性监测 [胡红岩, 任相亮, 马小艳, 马亚杰, 宋贤鹏, 王丹, 李欢欢, 马艳] 植物保护学报 2021 (4) 900-906
几种Bt复配杀虫剂对甘蓝小菜蛾的防治效果 [韩新才, 黄志农, 蔡福民, 肖国蓉, 徐尚斌, 张宁] 湖北农业科学 2004,2004 (6) 44-46
棉铃虫对三氟氯氰菊酯的抗性狭义遗传力及其与体重的相关性 [孟香清, 芮昌辉, 赵建周, 范贤林, 魏岑] 昆虫学报 2001,44 (2) 59-63
霍乱毒素对三氟氯氰菊酯抗性及敏感棉铃虫神经细胞L型钙通道的调节作用(英文) [赵强, 李杰, 刘燕强, 范贤林, 季青, 刘安西] 昆虫学报 2006,49 (1) 52-59
3种杀虫剂亚致死浓度对旋幽夜蛾幼虫解毒酶活性的影响 [张航, 杨安沛, 白微微, 高海峰, 李广阔, 王锁牢] 农药 2020 (11) 846-850
2.5%三氟氯氰菊酯乳油防治荔枝蝽蟓 [林仁魁, 蔡慧娟, 王惠媛, 付冬姬, 叶加树] 农药 2000,39 (6) 26-27
超临界流体萃取三氟氯氰菊酯及甲氰菊酯残留条件研究 [杨立荣, 张兴, 陈安良, 周一万] 农药 2005,44 (1) 16-18
5%三氟氯氰菊酯水乳剂的安全环保配方 [张保华, 潘淑翠, 王智, 王琼] 农药 2011,50 (11) 36-39
三氟氯氰菊酯对小鼠骨髓细胞微核及精子畸形和蓄积毒性的影响研究 [李玖营, 沈明浩] 中国畜牧兽医 2011,38 (9) 152-155
三氟氯氰菊酯微乳剂的相图研究 [夏茹, 吴彬, 张岭] 农药 2005,44 (2) 10-12

导出引用

计量

文章访问数: 5

HTML全文浏览量: 0

PDF下载量: 0

三氟氯氰菊酯对小鼠肝、肾的影响

相似文章

所属期刊

农药

推荐期刊

植物保护学报

农药