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乙羧氟草醚的合成

作  者:
白延海;李瑞军;洪广峰;田新慧
单  位:
郑州大学化学系郑州大学新药研究开发中心
关键词:
乙羧氟草醚;二苯醚;除草剂;合成
摘  要:
以间羟基苯甲酸和3,4-二氯三氟甲苯为原料,经过成盐、醚化、硝化、缩合4步反应得到乙羧氟草醚,所得产物化学结构经红外光谱、核磁共振谱及质谱等确证。反应总收率在75.0%以上,含量(HPLC)达89.0%。
译  名:
Synthesis of Fluoroglycofen-ethyl
作  者:
BAI Yan-hai, LI Rui-jun, HONG Guang-feng, TIAN Xin-hui (Department of Chemistry, New Drug Research & Development Center, Zhengzhou University, Zhengzhou 450052, China)
关键词:
fluoroglycofen-ethyl; diaryl ethers; herbicide; synthesis
摘  要:
Fluoroglycofen-ethyl was synthesized from starting materials m-hydroxybenzoic acid and 3,4-dichloro- benzotrifluoride via four steps including salification, etherification, nitration, condensation etc. The structure of target compound was confirmed by IR,1H-NMR and MS. Total yield was above 75.0%, purity was 89.0%.

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