Position: Home > Articles > Study on Hypolipidemic Effect of Root Extracts of Withanla somnifera(L) Dunal. Growing in Chongqing
FOOD SCIENCE
2008,29
(4)
361-365
引种新资源——印度人参根提取物降血脂作用研究
作 者：
周才琼;张宝勇
单 位：
西南大学食品科学学院
关键词：
引种新资源;印度人参;根提取物;降血脂作用
摘 要：
目的:研究引种新资源印度人参根提取物的降血脂作用。方法:将50只小鼠随机分成阴性对照组(普通饲料)、阳性对照组(脂肪乳剂)和高、中、低剂量组(提取物+脂肪乳剂),分笼喂养30d,测定实验前后血清TC、TG、LDL-C和HDL-C,并处死动物观察肝脏组织病理学变化。结果:印度人参根提取物可明显降低高脂饮食所致高血脂小鼠TC、TG和LDL-C含量(p<0.05),升高HDL-C含量(p<0.05),可降低高脂小鼠肝组织中脂肪细胞数量。结论:引种新资源——印度人参根提取物有辅助降血脂作用。
译 名：
Study on Hypolipidemic Effect of Root Extracts of Withanla somnifera(L) Dunal. Growing in Chongqing
作 者：
ZHOU Cai-qiong,ZHANG Bao-yong (College of Food Science, Southwest University, Chongqing 00716, China)
关键词：
induced new resource;Withania somnifera(L.);root extracts;hypolipidemic effect
摘 要：
Objective: To study the hypolipidemiceffect of root extracts of Withania somnifera(L.) growing in Chongqing. Methods: Fifty Kunming mice were divided into negative control group(normal feed), positive control group(fat emulsion) and high, moderate and low dose groups(extract+fat emulsion). Each group was fed 30d. The level of total cholesterol(TC), triglyceride(TG), low density lipoprotein cholesterol(LDL-C) and high lipoprotein cholesterol(HDL-C) were determined at the beginning and end of test. At the end of 30d, all mice were killed to observe the change of liver by laser confocus. Results: Root extracts of Withania somnifera(L.) can evidently decrease TC, TG and LDL-C level but increase HDL-C level in high blood lipids mice induced by fat emulsion(p<0.05), with fat drip reduced in the liver. Conclusion: Root extracts of Withania somnifera(L.) growing in Chongqing have hypolipidemic effect.
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