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当前位置: 首页 > 文章 > Morphological Changes in Hippocampus and Prefrontal Cortex of Confined Sows with Prolonged Pupillary Light Reflex 东北农业大学学报(英文版) 2016,23 (3)
Position: Home > Articles > Morphological Changes in Hippocampus and Prefrontal Cortex of Confined Sows with Prolonged Pupillary Light Reflex Journal of Northeast Agricultural University(English Edition) 2016,23 (3)

Morphological Changes in Hippocampus and Prefrontal Cortex of Confined Sows with Prolonged Pupillary Light Reflex

作  者：
Lv Fang-lu;Xiang Li;Jianhong Li;Shiquan Cui;Honggui Liu;Jun Ba
单  位：
College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, Chin;Heilongjiang Polytechnic College, Harbin 150010, China;College of Animal Science and Technology, Northeast Agricultural University, Harbin 150030, China;College of Life Sciences, Northeast Agricultural University, Harbin 150030, China
关键词：
sows;hippocampus;plrt;the results;prefrontal cortex;morphological change
摘  要：
Human depression patients often show abnormal pupillary reflex with morphological changes in hippo campus and prefrontal cortex. This study aimed to find the relationship between the prolonged pupillary light reflex (PLR) which had been shown by confined sows with chronic stress or depression and morphological changes in brain, in order to provide theoretical basis for that the confined environment should lead to sows' depression. A total of 637 sows of Durac, Landrace and Large White breeds with various parities were observed, and the pupil light reflex (PLR) was measured and the actual pupillary light reflex time (PLRT) were recorded. All the PLRTs were grouped based on the results of confidence interval: t>10% as group A, 5%10%) pathological change was found in hippocampus, however, as PLRT increased from group B to group D, pathological changes in hippocampus tissues tended to be deteriorated with the increase of inflammatory cells and nuclear pyknosis phenomena. The same as those shown in hippocampus as the increasing of PLRT from groups A to D, more inflammatory cells appeared in prefrontal cortex for groups B and D. The results suggested that the tissue lesions of hippocampus and prefrontal cortex of the confined sows with prolonged PLRT might be the results of chronic stress or depression.

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