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Position: Home > Articles > Study on the pigeon paramyxovirus inactivated vaccine of different water/oil ratio Acta Agriculturae Shanghai 2015 (5) 27-31

鸽副黏病毒油乳剂灭活疫苗不同水油比的研究

作  者:
蒋凤英;张俊平;何锡忠;张春玲;李春华;周宗清;杨惠萍;倪建平
单  位:
上海市农业科学院畜牧兽医研究所
关键词:
鸽副黏病毒;油乳剂灭活疫苗;水油比
摘  要:
为了减少鸽副黏病毒油乳剂灭活疫苗的副作用,保证疫苗的安全性及免疫效果,利用分离到的鸽Ⅰ型副黏病毒(S-1株)作为抗原,配制了不同水油比的疫苗,对疫苗的物理性状、安全性、效力试验及免疫效果进行观察,探究疫苗不同水油比的差异。结果表明:该疫苗的水油乳化比为1:4时,疫苗的稳定性最好、免疫效果最佳。
译  名:
Study on the pigeon paramyxovirus inactivated vaccine of different water/oil ratio
作  者:
JIANG Feng-ying;ZHANG Jun-ping;HE Xi-zhong;ZHANG Chun-ling;LI Chun-hua;ZHOU Zong-qing;YANG Hui-ping;NI Jian-ping;Animal Husbandry and Veterinary Research Institute,Shanghai Academy of Agricultural Sciences;
关键词:
Pigeon paramyxovirus;;Oil emulsion inactivated vaccine;;Ratio of water/oil
摘  要:
In order to reduce the side-effects of pigeon paramyxovirus oil emulsion inactivated vaccine and ensure the safety and immune effect of vaccine,the isolated pigeon paramyxovirus S-1 strain was used as the antigen to prepare with different water/oil ratio.The physical characteristics,safety,efficacy and immune effect of the vaccine were observed to explore the vaccine differences of different water/oil ratio.The results indicated that the vaccine has the best stability and immune effect when the water/oil ratio is 1:4.

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