译 名：
The inhibiting effects of Herba Cistanche on begnin prostatic hyperplasia
作 者：
SUN Wei-dong1,Chen fei2,Sun yun2 (1.Yangzhou Hosp of Trad Chineses Med,Yangzhou 225009,China;2.Coll of Med,Yangzhou Univ,Yangzhou 225001,China)
关键词：
acteoside;begnin prostatic hyperplasia;androgen receptor;transformation growth factorⅠrecptor
摘 要：
The BPH rat model was induced by subcutaneous injection of testosterone propionate,and two dose groups of acteoside [40,20 mg(kg·d)-1] were administrated for 4 weeks,to observe the morphological change of the prostate gland by the microscope.AR and TGF-β1R expressions was examined by the immunity histochemistry.The inhibiting effects of acteoside distilled from Cistanche tubulosa.on begnin prostatic hyperplasia(BPH) were investigated.The acteoside could obviously reduce the prostate gland fresh weight index.Compared with the the model group,the difference was obvious (P<0.01).AR and TGF-βR1 expressions reduced in the prostate gland epidermis cell nucleus in high dose group.Compared with the the model group,the difference was obvious(P<0.01).Acteoside had the function of inhibiting the experimental models'BPH.
