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Position: Home > Articles > Protective Effects of Qishen Oral Solution on Immunosuppressed Mice Chinese Agricultural Science Bulletin 2013 (11) 24-28

芪参口服液对免疫功能低下小鼠的保护作用

作  者:
王建舫;贾梦然;胡艳姣;吴洁;高会军;穆祥
单  位:
北京农学院兽医学;石家庄华牧牧业有限责任公司兽药分公司
关键词:
芪参口服液;环磷酰胺;小鼠;免疫力;保护作用
摘  要:
为探讨芪参口服液对免疫力低下小鼠的保护作用,用环磷酰胺造小鼠免疫力低下模型,同时灌胃给芪参口服液,分别测定小鼠的胸腺系数、脾脏系数、血清溶血素水平、血清IL-2含量和网状内皮细胞的吞噬能力。结果显示:芪参口服液能够显著增加免疫功能低下小鼠的胸腺系数和脾脏系数,显著增强其血清溶血素生成水平和网状内皮细胞的吞噬能力(P<0.01)。表明芪参口服液对免疫功能低下小鼠具有保护作用。
译  名:
Protective Effects of Qishen Oral Solution on Immunosuppressed Mice
作  者:
Wang Jianfang 1 , Jia Mengran 1 , Hu Yanjiao 1 , Wu Jie 1 , Gao Huijun 2 , Mu Xiang 1 (1 Beijing Key Laboratory of Traditional Chinese Veterinary Medicine, Beijing University of Agriculture , Beijing 102206 ; 2 Shijiazhuang Huamu Animal Husbandry Co., Ltd., Animal Pharmaceutical Sub Co., Shijiazhuang 050061)
关键词:
Qishen Oral Solution; cyclophosphamide; mice; immunity; protective effects
摘  要:
In order to explore the protective effects of Qishen oral solution on immunosuppressed mice, Qishen oral solution was ingested to mice whose immunity function was depressed by cyclophosphamide. Thymus index, spleen index, the serum level of hemolysin, the serum content of IL-2 and phagocytic index of reticuloendothelial cell were measured. The results showed that Qishen oral solution could significantly increased thymus index, spleen index, the serum level of hemolysin, and phagocytic index of reticuloendothelial cell in immunosuppressed mice (P<0.01). In conclusion, Qishen oral solution possessed the protective effects on immunosuppressed mice.

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