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Position: Home > Articles > Experimental Study on Anti-inflammatory Effects of the Crude Extraction of Cucurbita pepo cv Progress in Veterinary Medicine 2004,25 (5) 108-109

苦味西葫芦粗提物抗炎作用的实验研究

作  者:
张艳萍;邓旭明;祝万菊;王学林
单  位:
解放军军需大学军事兽医系
关键词:
苦味西葫芦;抗炎;角叉菜胶;炎症
摘  要:
研究苦味西葫芦粗提物的抗炎作用。采用醋酸诱导小鼠腹腔毛细血管通透性增加、角叉菜胶诱导大鼠足跖肿胀及棉球诱导大鼠肉芽肿模型研究苦味西葫芦粗提物的抗炎作用。ip苦味西葫芦粗提物(小鼠4 g/kg,大鼠2.8 g/kg)可显著抑制小鼠腹腔毛细血管通透性增强及大鼠棉球肉芽肿(P<0.05)、ip苦味西葫芦粗提物(大鼠1.4 g/kg及2.8 g/kg)均能显著抑制角叉菜胶诱导大鼠足跖肿胀(P<0.05)。苦味西葫芦粗提物具有抗急、慢性炎症作用。
译  名:
Experimental Study on Anti-inflammatory Effects of the Crude Extraction of Cucurbita pepo cv
作  者:
ZHANG Yan-ping,DENG Xu-ming,ZHU Wan-ju,WANG Xue-lin(Faculty of Military Veterinary, Quarter Master University of PLA, Changchun, Jiling, 130062, China)
关键词:
Cucurbita pepo cv; anti-inflammatory ;carrageenan( car); inflammation
摘  要:
To study the anti-inflammatory effects of the crude extraction of Cucurbita pepo cv . Three types of models o acute or chronic inflammation were used to observe the anti-inflammatory effect of the crude extraction. Results: The experimental results suggested that the crude extraction (mice 4 g/kg, rats 2. 8 g/kg) has obvious inhibition for mice abdominal capillary permeability and rats cotton-pellet granulation tumor ( P < 0. 05) ;the crude extraction(rats 1. 4 g/kg, 2. 8 g/kg) could inhibit the swelling of rats paw caused by carrag-eenan(p<0. 05). the crude extraction could effectively treat acute and chronic inflammation.

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