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当前位置: 首页 > 文章 > 黄芪多糖与庆大霉素肌肉注射治疗犬脾虚泄泻证的比较 中国兽医学报 2014,34 (2) 293-296
Position: Home > Articles > Treatment effect of intramuscular injection of Astragalus polysaccharide and gentamicin on splenasthenic diarrhea in canine Chinese Journal of Veterinary Science 2014,34 (2) 293-296

黄芪多糖与庆大霉素肌肉注射治疗犬脾虚泄泻证的比较

作  者：
曹立亭;彭代国;张媛媛;仲崇华;马跃
单  位：
西南大学荣昌校区动物医学系;农标普瑞纳(重庆)饲料有限公司
关键词：
黄芪多糖注射液;庆大霉素;犬脾虚泄泻证;治疗效果
摘  要：
以犬为研究对象,探讨黄芪多糖注射液肌肉注射对犬脾虚泄泻证的临床治疗效果。24只健康本地犬饲养1周后灌胃番泻叶水煎剂人工复制脾虚泄泻证病理模型,造模成功后随机分为3组:黄芪多糖注射液治疗组肌肉注射黄芪多糖注射液0.25mL/kg,2次/d;庆大霉素组肌肉注射庆大霉素注射液0.2mL/kg,2次/d;病理对照组不作任何处理;同时设立4头健康犬作为空白对照,造模期间灌胃生理盐水。治愈后检测试验犬体质量、三大临床指标、白细胞、红细胞、血红蛋白及脾脏指数,并进行统计分析。结果表明,黄芪多糖注射液治疗组治愈后白细胞、血红蛋白、红细胞恢复较快,平均日增重及脾脏指数显著高于庆大霉素治疗组(P<0.05);三大临床指标各治疗组差异不显著(P>0.05)。说明黄芪多糖注射液可用于临床治疗动物脾虚泄泻证。
译  名：
Treatment effect of intramuscular injection of Astragalus polysaccharide and gentamicin on splenasthenic diarrhea in canine
作  者：
CAO Li-ting;PENG Dai-guo;ZHANG Yuan-yuan;ZHONG Chong-hua;MA Yue;Department of Veterinary Medicine,Southwest University,Rongchang Campus;Agribrands Purina(Chongqing) Feedmill Co.,Ltd.;
关键词：
Astragalus polysaccharide injection;;gentamycin;;canine splenasthenic diarrhea;;treatment effectiveness
摘  要：
The research was designed to investigate the effect of intramuscular injection of Astragalus polysaccharide(APC)for the treatment of splenasthenic diarrhea in canine.Twenty-four local healthy dogs were administrated intragastricly senna leaf water decoction to make pathogenic model of splenasthenic diarrhea.After that,all the experimental dogs were randomly divided into 3 groups:group of APC was intramuscularly injected 0.25mL/kg·body weight of APC injection,2 times/d;group of gentamicin was injected 0.2mL/kg·body weight of gentamycin,2 times/d;for the pathological control group receiving no treatment.At the same time,4 dogs were used for the blanked group administrating intragastricly physiological saline in the period of pathogenic model building.Body weight,three main clinical indicators,the number of white blood cells,red blood cells and hemoglobin and spleen index were detected after treated.The results indicated that the number of white blood cells,hemoglobin and red blood cells recovered to normal levels in a short time after the treatment of APS,average daily gain of body weight and spleen index were significantly higher than the treatment of gentamycin(P<0.05).But there was no significant difference in the three main clinical indicators between the groups of APC injection and gentamicin(P >0.05).It indicted that APS intramuscular injection could be used for the treatment of splenasthenic diarrhea in canine.

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