中国农业科学院农业信息研究所 中国农学会
Agricultural Information Institute of CAAS China Association of Agricultural Science Societies
En
Ch
中国农业科学院农业信息研究所 中国农学会 主办

AI检索

订阅

返回顶部
当前位置: 首页 > 文章 > 毒死蜱和阿特拉津对鲤肝脏的影响 东北农业大学学报 2015 (3) 67-73
Position: Home > Articles > Effect of atrazine and chlorpyrifos on common carp's liver Journal of Northeast Agricultural University 2015 (3) 67-73

毒死蜱和阿特拉津对鲤肝脏的影响

作  者：
韩英;郝其睿;魏菁;赵荣伟;牟振波;徐革锋;刘洋
单  位：
中国水产科学研究院黑龙江水产研究所;东北农业大学动物科学技术学院;大连出入境检验检疫局
关键词：
阿特拉津;毒死蜱;鲤;肝脏
摘  要：
探讨阿特拉津(Atrazine,ATR)、毒死蜱(Chlorpyrifos,CPF)及其混合物对鲤(Cyprinus carpio L.)肝脏和血液相关指标的影响。将实验鲤分别暴露于不同浓度的阿特拉津、毒死蜱及其混合物中,并分别于175、350和525 d采集其肝组织、血液等样品。结果表明,阿特拉津和毒死蜱在鲤肝组织中均有残留,残留量随暴露时间及浓度的增加而降低;与对照组比较,各染毒组碱性磷酸酶、谷丙转氨酶及血糖水平显著升高,总蛋白、白蛋白水平下降,抗氧化能力下降,且毒死蜱与阿特拉津混合后毒性作用更强,说明两者的毒性有叠加作用;染毒后,肝脏ER-α和VTG-II基因表达水平升高。结果显示,鲤肝脏对阿特拉津和毒死蜱有较强的代谢能力,阿特拉津和毒死蜱在鲤肝脏无富集作用;阿特拉津和毒死蜱使鲤肝功能受损,抗氧化能力降低;ER-α和VTG-II基因的高调表达显示出阿特拉津和毒死蜱对鲤亦有环境雌激素作用。
译  名：
Effect of atrazine and chlorpyrifos on common carp's liver
作  者：
HAN Ying;HAO Qirui;WEI Jing;ZHAO Rongwei;MOU Zhenbo;XU Gefeng;LIU Yang;School of Animal Sciences and Technology, Northeast Agricultural University;Heilongjiang Fisheries Research Institute, Chinese Academy of Fishery Sciences;Entry-Exit Inspection and Quarantine Bureau;
关键词：
atrazine;;chlorpyrifos;;common carp;;liver
摘  要：
In this study our purpose is to discuss the effects of atrazine and chlorpyrifos and their mixture to related index of common carp's liver and blood. Exposeed experimental carps respectively in atrazine, chlorpyrifos and their mixture of different concentrations, and collected samples of common carp's liver and blood at 175, 350 and 525 d. Results showed that both atrazine and chlorpyrifos had residual in common carp's liver and the residual quantity reduced with the exposure time and the concentration increasing. Compared to the control group, the alkaline phosphatase, glutamic-pyruvic transaminase and blood glucose levels of each infected group had significant rise, while the total protein and albumin levels declined. Moreover, the toxicity of the mixture of atrazine and chlorpyrifos was stronger than that prior to the blending, which illustrated the toxicity of the two have superposition. After infected,the expression level of ER-α and VTG-II in liver went up. The experimental results expressed that the common carp's liver had strong metabolic capability to atrazine and chlorpyrifos and the two had no concentration in common carp's liver. Atrazine and chlorpyrifos caused the function of commone carp's liver damaged and reduced its antioxidant capacity. The high expression levels of ER-α and VTG-II showed that atrazine and chlorpyrifos had environmental estrogen effects to common carp as well.

相似文章

导出引用
计量
文章访问数: 8
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊

友情链接Friendly link
农业信息研究所Agricultural information institute 农业智能知识服务平台Agricultural intelligent knowledge service platform 农业学术服务平台Agricultural Knowledge Service System 中国知网CNKI 维普网VIP 万方WANFANG DATA
联系我们Contact us

电话Tell：010-82109652-808

邮箱E-mail：agrijournal@caas.cn

服务Service
关于我们About us 意见建议Opinions and suggest
版权说明Copyright
单位：中国农业科学院农业信息研究所 中国农学会 © 2017中国农业科学院农业信息研究所 ICP备案号：京ICP备09089781号-46