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Position: Home > Articles > Formation Mechanisim of the Caculus Bovis in the External Artificial Gallbladder Chinese Journal of Animal and Veterinary Sciences 2004,35 (1) 50-54

牛体外牛黄发生器内成黄机制的研究

作  者：
李建基;闫振贵;刘翠艳;刘俊栋;李强
单  位：
山东农业大学动物科技学院
关键词：
牛;牛黄;培植;体外;牛黄发生器(人工胆囊)
摘  要：
利用5头健康黄牛同时施行了牛体外牛黄发生器内培植牛黄手术和肝脏内胆管插管手术,以探讨牛黄的形成机理。研究结果表明:在牛黄菌种的作用下,胆汁的理化特性首先在肝内胆管发生改变,转变为成黄胆汁;胆汁进入胆囊后,黏蛋白含量和细菌的数量迅速增加,结果导致胆汁的黏度升高,胆酸含量和pH值下降,这加速了牛黄小颗粒的形成;在牛黄发生器内,胆汁的黏度和pH值下降,这促进牛黄小颗粒的沉降、聚集和附着,从而减少了牛黄的丢失,提高了牛黄产量。牛的体重大,分泌的胆汁多,牛黄产量高。
译  名：
Formation Mechanisim of the Caculus Bovis in the External Artificial Gallbladder
作  者：
LI Jian-ji,YAN Zhen-gui,LIU Cui-yan,LIU Jun-dong,LI Qiang(College of Animal Science and Technology,Shandong Agricultural University,Taian 271018,China)
关键词：
Cattle;External;Cultivate;Calculus Bovis;Artificial gallbladder
摘  要：
Five healthy cattle were used to cultivate the Calculus Bovis in the external artificial gallbladder(EAG)and were simultaneously performed catheterization of the hepatobiliary ducts for draining the liver bile.During the period of cultivating the Calculus Bovis,the physical and chemical characters of the bile(including the intrahepatic bile and the gallbladder bile and the EAG bile)were analyzed in order to investigate the mechanism of formation of the Calculus Bovis in the EAG.The results showed that as inoculating the E.colic in the bile,the physical and chemical characters changed originally in the intrahepatic bile,the normal bile were changed into the Calculus Bovis-forming bile.While the bile moved from the intrahepatic duct into gallbladder,the quantity of the mucin and E.coli increased,which made the viscosity of bile increasing and the pH value and the content of cholic acid in the bile decreasing.The formation of the Calculus Bovis microgranules were thus accelerated.The viscosity and pH value of the bile in the EAG were decreased,resulting in the Calculus Bovis microgranules to sink and assemble and adhere to the Calculus Bovis' carrier easily,which prevented the Calculus Bovis granules from moving into the duodenum and improved the output of the Calculus Bovis.The more the body weight of cattle,the more the quantity of bile,and then the higher the output of Calculus Bovis.

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