译 名:
Spectinomycin Hydrochloride and Lincomycin Hydrochloride Soluble Powder Preparation Technology and Stability Study
作 者:
CHENG Haipeng;YANG Jinyue;GENG Jiurong;Beijing Kang Mu Biotechnology Co., LTD;
关键词:
Spectinomycin hydrochloride;;Lincomycin hydrochloride;;Preparation process;;Clinical application
摘 要:
Spectinomycin hydrochloride and lincomycin hydrochloride soluble powder is one of the few compound antibiotic veterinary drugs listed in the Chinese Veterinary Pharmacopoeia.Its antibacterial spectrum and activity are broader and stronger than that of monotherapy preparation, and it is one of the models of antibiotic combined application. Some products on the market adopt grinding technology to increase the solubility while others adopt the addition of anticaking agent to prevent binding, and a small number of products are sterilized by irradiation for injection. In this paper, the preparation technology and stability of spectinomycin hydrochloride and lincomycin hydrochloride soluble powder were studied in order to provide some guidance for the process and field use of this product.