中国农业科学院农业信息研究所 中国农学会
Agricultural Information Institute of CAAS China Association of Agricultural Science Societies
En
Ch
中国农业科学院农业信息研究所 中国农学会 主办

AI检索

订阅

返回顶部
当前位置: 首页 > 文章 > 硫酸铜日粮对肉鸡肝线粒体呼吸复合物活性的影响 畜牧与兽医 2009,41 (1) 18-21
Position: Home > Articles > Influence of high-copper diet on respiratory chain complex activities in liver mitochondria of broiler Animal Husbandry & Veterinary Medicine 2009,41 (1) 18-21

硫酸铜日粮对肉鸡肝线粒体呼吸复合物活性的影响

作  者：
曹华斌;苏荣胜;郭剑英;李英;潘家强;李成梅;唐兆新
单  位：
华南农业大学兽医学院
关键词：
肉鸡;高铜日粮;线粒体复合物;活性
摘  要：
采用玉米-豆粕型饲粮研究铜(源于硫酸铜)对肉鸡肝细胞线粒体呼吸链复合物活性的影响。在对照组(Cu 11 mg/kg,称试验组A)基础上设高铜组3个(含Cu分别为110,220和330 mg/kg,分别称为试验组B、C、D),试验期60 d。在12,24,36,48,60日龄采集肝脏,提取线粒体,测定线粒体复合物Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ活性变化。结果表明,A组和B组线粒体复合物Ⅰ、Ⅱ、Ⅲ、Ⅳ、Ⅴ活性呈增加趋势;C组和D组活性有减弱表现,尤其是48 d之后,比各组的试验前期下降明显(P<0.05)。说明高铜日粮在一定程度上对线粒体复合物活性是有利的,但过高的铜添加日粮(≥220 mg/kg)可降低肉鸡肝细胞线粒体呼吸链复合物功能活性,可以推测线粒体是机体铜过量状态下侵害的靶部位之一,而且能作用于线粒体各个复合物,造成线粒体呼吸功能减弱,呼吸链中电子传递发生故障,从而影响线粒体功能的正常发挥。
译  名：
Influence of high-copper diet on respiratory chain complex activities in liver mitochondria of broiler
作  者：
CAO Hua-bin,SU Rong-sheng,GUO Jian-ying,LI Ying,PAN Jia-qiang,LI Cheng-mei,TANG Zhao-xin(College of Veterinary Medicine,South China Agricultural University,Guangzhou 510642,China)
关键词：
broilers;high-copper diet;mitochondrial complex;activity
摘  要：
The experiment was conducted to understand the influence of high-copper(from Copper sulfate) diet on mitochondrial complex from broiler hepatocyte.Based on the control group(Cu 11 mg/kg,group A),three experimental groups were set up.The contents of Cu were 110 mg/kg(group B),220 mg/kg(group C) and 330 mg/kg(group D),respectively.All of the broilers were fed with corn-soybean meal for 60 days,and the activities of mitochondrial complex from broilers' hepatocyte were assayed at 12,24,36,48 and 60 day-old.The result showed that the high-copper diet had an obvious influence on liver mitochondrial complex.The activities of each complex in group A and B had a tendency of increasing,especially in group B(P<0.05),but the activities were subject to decrease in group C and D(P<0.05).The above changes were more significant on the later stage of whole experiment(after 48 day-old).The results indicated that high-copper diet could be helpful to liver mitochondrial complex of broiler to some extent,but too high-copper diet(≥220 mg/kg) might degrade the activity of mitochondrial complex.It was presumed that mitochondria was the invasive target under the condition of copper excess,and when mitochondrial complex was damaged,respiratory function of mitochondria was decreased and the electron transfer in respiratory chain might break down.

相似文章

导出引用
计量
文章访问数: 11
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊

友情链接Friendly link
农业信息研究所Agricultural information institute 农业智能知识服务平台Agricultural intelligent knowledge service platform 农业学术服务平台Agricultural Knowledge Service System 中国知网CNKI 维普网VIP 万方WANFANG DATA
联系我们Contact us

电话Tell：010-82109652-808

邮箱E-mail：agrijournal@caas.cn

服务Service
关于我们About us 意见建议Opinions and suggest
版权说明Copyright
单位：中国农业科学院农业信息研究所 中国农学会 © 2017中国农业科学院农业信息研究所 ICP备案号：京ICP备09089781号-46