Effects of Sporoderm-broken Ganoderma Spores Cultivated by Logs on the Immune Function in Mice

WU Xue-qian;WU Xue-liang;LOU Li-ming;ZHAO Zhong-shan;CHEN Ru-chu;XU Juan;LI Qing-qing;XU Hai-shun;DANG Ya-li;Zhejiang Wuyangtang Pharmaceutical CO.,LTD.Edible fungus Research and Development Centre in Lishui City;Zhejiang Academy of Medical Science;

Sporoderm-broken Ganoderma spores cultivated by logs;;Immune function;;Mice

To study the immune function of sporoderm- broken Ganoderma spores cultivated by logs,three concentrations of sporoderm-broken Ganoderma spores cultivated by logs and a control group were studied by a serial experiments including ConA-induced lymphocyte transformation test,sheep red blood cells induced delayed type hypersensitivity(DTH) test,serum hemolysin and antibody producing cells determination,phagocytosis test of chicken red blood cells by peritoneal macrophages,carbon clearance and NK cells activities assay,and organ weight measurement in mice.The results showed that all dose groups were able to significantly improve the proliferation of splenic lymphocytes,that the high dose group could significantly improve left-hind feet thickness of mice,and that the medium and high dose groups could significantly improve the numbers of plague forming cells in mice compared with the control group.In conclusion,the sporoderm-broken Ganoderma spores cultivated by logs could improve the immune function in mice.