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Position: Home > Articles > Curcumin attenuates ochratoxin A and hypoxia co-induced liver injury in grass carp (Ctenopharyngodon idella) by dual targeting endoplasmic reticulum stress and apoptosis via reducing ROS content. Journal of Animal Science and Biotechnology 2024,15 (1)

Curcumin attenuates ochratoxin A and hypoxia co-induced liver injury in grass carp (Ctenopharyngodon idella) by dual targeting endoplasmic reticulum stress and apoptosis via reducing ROS content.

作  者:
Liangqin Wu;Piao Zhao;Pei Wu;Wei‐Dan Jiang;Liu Yang;Hongmei Ren;Xiao‐Wan Jin;Xiaoqiu Zhou;Lin Fen
关键词:
Apoptosis;Curcumin;Endoplasmic reticulum stress;Grass carp;Hypoxia;Ochratoxin A;Oxidative damag
摘  要:
Ochratoxin A (OTA) is a toxin widely found in aquafeed ingredients, and hypoxia is a common problem in fish farming. In practice, aquatic animals tend to be more sensitive to hypoxia while feeds are contaminated with OTA, but no studies exist in this area. This research investigated the multiple biotoxicities of OTA and hypoxia combined on the liver of grass carp and explored the mitigating effect of curcumin (CUR).

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