Immune Effects of Recombinant Avian Influenza Inactivated Vaccine on Cherry Valley Ducks and SPF Ducks

Qi Lihong;Wang Youling;Liu Tao;Shao Guibin;Xu Huaiying;Li Feng;Ju Yan;Shao Guiping;Li Xia;Ai Wu;Institue of Poultry Science,Shandong Academy of Agricultural Sciences, Shandong Provincial Key Laboratory of Immunity and Diagnosis of Poultry Diseases;Juxian Zhongxin Farming Limited Company;

Avian influenza inactivated vaccine(H5N1,Re-6 strain + Re-8 strain);;Cherry Valley ducks;;SPF ducks;;Immune effect

To investigate the immune effects of recombinant H5N1 subtype avian influenza inactivated vaccine(H5N1,Re-6 strain + Re-8 strain) and provide clinical basis for formulating the reasonable avian influenza vaccine immune program,thirty 14 days old Cherry Valley ducks and thirty 14 days old SPF ducks were immunized with H5N1 subtype AI(Re-6 strain + Re-8 strain) inactivated vaccine of 0. 4 m L each duck. To 28 days old,Cherry Valley ducks were randomly divided into two groups of A and B,and SPF ducks were randomly divided into two groups of C and D. Each group had 15 ducks. The Cherry Valley ducks in B group and SPF ducks in D group were immunized with 0. 5 m L H5N1 inactivated vaccine again each duck.The serum sample of each duck was separately collected and detected every week from 14 days old to 56 days old. It was showed that the immune effects were different for different species of ducks. The most suitable time of the first immunization was from 7 days old to 10 days old. For Cherry Valley ducks,immune one time was enough.