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Position: Home > Articles > in vivo Anti-tumor Activity of Total Saponins from Asparagus officinalis FOOD SCIENCE 2010,31 (13) 273-275

芦笋总皂苷抗肿瘤作用研究

作  者:
宋擎;柴秋彦;张立伟
单  位:
山西大学分子科学研究所;山西省医药与生命科学研究院
关键词:
芦笋;总皂苷;抗肿瘤
摘  要:
利用荷瘤小鼠观察研究芦笋总皂苷对移植性肿瘤S180、H22的体内抗肿瘤活性和对免疫器官质量的影响。结果表明:芦笋总皂苷对S180和H22荷瘤小鼠的肿瘤生长有明显抑制作用,高剂量组对S180和H22抑瘤率分别达到39.53%(P<0.05)和34.81%(P<0.01),并呈现良好的量效关系。
译  名:
in vivo Anti-tumor Activity of Total Saponins from Asparagus officinalis
作  者:
SONG Qing1,CHAI Qiu-yan2,ZHANG Li-wei1, (1. Institute of Molecular Science, Shanxi University, Taiyuan 030006, China ; 2. Shanxi Academy of Medicine and Life Science, Taiyuan 030006, China )
关键词:
Asparagus officinalis;total saponins;anti-tumor activity
摘  要:
The anti-tumor activity and immune regulation activity of total saponins from Asparagus officinalis were investigated by determining tumor weight and immune organ weight. The results indicated that total saponins from Asparagus officinalis had significant dose-dependent inhibitory effects on the growth of sarcoma S180 (S180) and hepatoma H22 (H22) cells implanted into healthy mice. The inhibition rate in high-dose group was 39.53% (P < 0.05) on S180 and 34.81% (P < 0.01) on H22 cells.

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