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Position: Home > Articles > Studies on the thermal decomposition characteristics of Quinolone drugs of Pipemidic Acid and Norfloxacin Journal of Northwest A & F University(Natural Science Edition) 2004,32 (9) 131-134

喹诺酮类(吡哌酸、诺氟沙星)药物的热分解特性研究

作  者:
甄宝勤;朱小梅;韩森
单  位:
陕西理工学院化学系
关键词:
差示扫描量热法(DSC);热重法(TG);微分热重法(DTG);热分解特性;吡哌酸;诺氟沙星
摘  要:
 分别采用差示扫描量热法(DSC)、热重法(TG)和微分热重法(DTG),研究了喹诺酮类(吡哌酸、诺氟沙星)抗菌药的热分解动力学过程,计算了其热分解动力学参数——活化能(E),分析了其热分解机理,并剖析了喹诺酮类药物有机结构上的差异。
译  名:
Studies on the thermal decomposition characteristics of Quinolone drugs of Pipemidic Acid and Norfloxacin
作  者:
ZHEN Bao-qin,ZHU Xiao-mei,HAN Sen(Deparment of Chemistry,Shaanxi University of Technology,Hanzhong,Shaanxi 723001,China)
关键词:
DSC;TG;DTG;thermal decomposition characteristics;Pipemidic Acid;Norfloxacin
摘  要:
The thermal characteristics of Quinolone drugs of Pipemidic Acid and Norfloxacin were analyzed by DSC (differentia scanning calorimetry),TG (thermogravimetry),DTG (differential thermogravimetry).The thermal kinetic parameter-energy of activation (E) was calculated as well.The thermal decomposition characteristics and the difference of Quinolone drugs in organic structure were analyed as well.

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