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Position: Home > Articles > Optimization of Ultrasonic-assisted Extraction of Total Flavonoids from Artemisia lavandulaefolia Using Response Surface Methodology FOOD SCIENCE 2010,31 (8) 38-42

响应面法优化野艾蒿总黄酮的超声波提取工艺

作  者:
熊子文;罗丽萍;张丽丽
单  位:
南昌大学生命科学与食品工程学院
关键词:
野艾蒿;总黄酮;响应曲面法;超声波法
摘  要:
为确定野艾蒿中总黄酮超声波提取的最佳工艺条件,以总黄酮得率为指标,采用响应面法对主要工艺参数进行优化并得到回归模型。结果表明:最优工艺条件为超声时间36.7min、提取温度74.99℃、乙醇溶液体积分数71.78%、液固比65.68:1(mL/g),在此工艺条件下的总黄酮得率为2.80%。回归模型的预测值与实测值的相对误差为1.1%,该回归方程与实际情况拟合较好。
译  名:
Optimization of Ultrasonic-assisted Extraction of Total Flavonoids from Artemisia lavandulaefolia Using Response Surface Methodology
作  者:
XIONG Zi-wen,LUO Li-ping,ZHANG Li-li(College of Life Science and Food Engineering,Nanchang University,Nanchang 330031,China)
关键词:
Artemisia lavandulaefolia;total flavonoids;response surface analysis methodology;ultrasonic-assisted extraction
摘  要:
Ethanol aqueous solution was used to extract total flavonoids from Artemisia lavandulaefolia under ultrasonic assistance.To optimize extraction yield of total flavonoids,30 experiments resulting from a five-variable and four-level central composite design were first carried out;subsequently,experimental data obtained were subjected to multiple variable regression fitting to establish a mathematical model for extraction yield of total flavonoids as a response to 5 variables and a significance test was performed for the model;and finally response surface analysis was conducted for investigating the interaction effects of 5 variables on extraction yield of total flavonoids.Results showed that the developed model could describe the relationship between extraction yield of total flavonoids and 5 variables such as ultrasonic treatment time,extraction temperature,ethanol concentration in aqueous solution and solid/liquid ratio very well.The optimal values of the variables were as follows:ultrasonic treatment time 36.7 min,extraction temperature 74.99 ℃,ethanol concentration in aqueous solution 71.78%,and solid/liquid ratio 1:65.68(g/mL).Under such conditions,the predicted value of extraction yield of total flavonoids was 2.8%,which was very consistent with the experimental value with a relative error of 1.1%.

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