中国农业科学院农业信息研究所 中国农学会
Agricultural Information Institute of CAAS China Association of Agricultural Science Societies
En
Ch
中国农业科学院农业信息研究所 中国农学会 主办

AI检索

订阅

返回顶部
当前位置: 首页 > 文章 > 地顶孢霉培养物对大鼠生长性能、血清与肝脏抗氧化及免疫指标的影响 动物营养学报 2016,28 (8) 2657-2666
Position: Home > Articles > Effects of Acremonium terricola Culture on Growth Performance,Antioxidant and Immune Indexes of Serum and Liver in Sprague Dawley Rats Chinese Journal of Animal Nutrition 2016,28 (8) 2657-2666

地顶孢霉培养物对大鼠生长性能、血清与肝脏抗氧化及免疫指标的影响

作  者：
李洋;林聪;许文斌;张幸怡;王一臻;高红;窦秀静;郝小燕;张永根
单  位：
东北农业大学动物科学技术学院
关键词：
地顶孢霉培养物;SD大鼠;生长性能;抗氧化;免疫
摘  要：
本试验旨在研究地顶孢霉培养物对大鼠生长性能、血清与肝脏抗氧化以及免疫指标的影响。选用体重相近的SD大鼠40只,随机分成5组,每组8个重复,每个重复1只大鼠。5组分别是对照组和4个不同地顶孢霉培养物剂量组(10、50、250和1 250 mg/kg BW组),连续灌胃21 d。结果表明:地顶孢霉培养物极显著提高大鼠的平均日增重(P<0.01);提高了大鼠肝脏指数、胸腺指数;提高了大鼠血清中总蛋白(TP)、白蛋白(ALB)、球蛋白(GLB)和葡萄糖(GLU)含量,降低了谷丙转氨酶(ALT)、谷草转氨酶(AST)活力和低密度脂蛋白(LDL)含量;提高了血清和肝脏中谷胱甘肽过氧化物酶(GSH-Px)活力和总抗氧化能力(T-AOC),降低丙二醛(MDA)含量,同时提高了肝脏中的总超氧化物歧化酶(T-SOD)含量;提高了血清免疫球蛋白A、免疫球蛋白G和免疫球蛋白M含量,同时提高血清和肝脏中白介素-4(IL-4)含量,降低白介素-1β(IL-1β)和白介素-17(IL-17)含量。综合各项指标,地顶孢霉培养物能够提高SD大鼠平均日增重,改善血清生化指标,提高大鼠机体抗氧化能力和免疫能力,其中以250 mg/kg BW的添加量为最佳。
译  名：
Effects of Acremonium terricola Culture on Growth Performance,Antioxidant and Immune Indexes of Serum and Liver in Sprague Dawley Rats
作  者：
LI Yang;LIN Cong;XU Wenbin;ZHANG Xingyi;WANG Yizhen;GAO Hong;DOU Xiujing;HAO Xiaoyan;ZHANG Yonggen;College of Animal Science and Technology,Northeast Agricultural University;
关键词：
Acremonium terricola culture;;Sprague Dawley rats;;performance;;antioxidant;;immunity
摘  要：
This study was aimed to investigate the effects of Acremonium terricola culture on growth performance,antioxidant and immune indexes of serum and liver in Sprague Dawley rats.Fourty Sprague Dawley rats with near weight were randomly divided into 5 groups with 8 replicates per group and 1 rat per replicate.One was control group and others were experimental groups with different doses of Acremonium terricola culture(10,50,250 and 1 250 mg/kg BW,respectively).Acremonium terricola culture was given corresponding medicines for 21 days via gavage.The results showed as follows:Acremonium terricola culture significantly improved average daily gain of rats(P < 0.01);improved liver and thymus indexes;improved serum total protein(TP),albumin(ALB),globulin(GLB) and glucose(GLU) contents,decreased serum activities of alanine transaminase(ALT) and aspertate transaminase(AST),and serum content of low-density lipoprotein(LDL);improved glutathione peroxidase(GSH-Px) activity and total antioxidant capacity(T-AOC),decreased malondialdehyde(M DA) content of serum and liver,and improved superoxide dismutase(T-SOD)activity of liver;increased serum contents of immunoglobulins A,M and G,increased interleukin-4(IL-4)content of serum and liver,and decreased contents of interleukin-1 β(IL-1 β) and interleukin-17(IL-17) of serum and liver.In conclusion,Acremonium terricola culture can improve average daily gain,biochemical indexes,antioxidant and immunity of serum and liver in Sprague Dawley rats,and the optimal supplemental level is 250 mg/kg body weight.[Chinese Journal of Animal Nutrition,2016,28(8):2657-2666]

相似文章

导出引用
计量
文章访问数: 8
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊

友情链接Friendly link
农业信息研究所Agricultural information institute 农业智能知识服务平台Agricultural intelligent knowledge service platform 农业学术服务平台Agricultural Knowledge Service System 中国知网CNKI 维普网VIP 万方WANFANG DATA
联系我们Contact us

电话Tell：010-82109652-808

邮箱E-mail：agrijournal@caas.cn

服务Service
关于我们About us 意见建议Opinions and suggest
版权说明Copyright
单位：中国农业科学院农业信息研究所 中国农学会 © 2017中国农业科学院农业信息研究所 ICP备案号：京ICP备09089781号-46