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Position: Home > Articles > Studies on Toxicological Effect of Sodium Pentachlorophenol on Bellamya purificata Journal of Hydroecology 2012 (4) 118-123

五氯酚钠对梨形环棱螺的毒理效应研究

作者：

王元川;侯建军;陈亚琼;舒晓;夏晓芬

单位：

湖北师范学院生命科学学院

关键词：

五氯酚钠;梨形环棱螺;急性毒性试验;毒理效应;精氨酸激酶

摘要：

采用在体暴露试验的方法,研究了不同浓度五氯酚钠(Na-PCP)在不同暴露时间(24、48、72和96 h)下对梨形环棱螺的急性毒性,以及Na-PCP对肝脏、鳃和腹足中精氨酸激酶(AK)活性的影响。结果显示,Na-PCP对梨形环棱螺的半致死浓度为0.411 mg/L,安全浓度为0.0411 mg/L;在Na-PCP暴露下,梨形环棱螺肝脏中单位蛋白AK活性在低浓度下被诱导增长,在高浓度下则出现被抑制的现象,鳃和腹足中单位蛋白AK活性伴随Na-PCP浓度的增加而下降,表现出时间剂量效应,且腹足中下降幅度相对鳃中较大。试验结果表明AK活性可以作为指示五氯酚钠对梨形环棱螺毒理效应的生物标志物。

译名：

Studies on Toxicological Effect of Sodium Pentachlorophenol on Bellamya purificata

作者：

WANG Yuan-chuan,HOU Jian-jun,CHEN Ya-qiong,SHU Xiao,XIA Xiao-fen(College of Life Sciences,Hubei Normal University,Huangshi 435002,P.R.China)

关键词：

Sodium pentachlorophenol;Bellamya purificata;acute toxicity test;toxicological effect;arginine

摘要：

An exposure experiment in vivo was carried out to study the acute toxicity of Sodium pentachlorophenol(Na-PCP) on Bellamya purificata and its effects on level of arginine kinase(AK) in liver,gill and gastropoda of B.purificata at different concentrations and exposure times(24,48,72 and 96 h).The results showed that the LC50 values of Na-PCP on B.purificata was 0.411 mg/L,and the safe concentration was 0.0411 mg/L;the activity of AK in liver of B.purificata was induced at low concentrations while inhibited at high concentrations,while the activities of AK in gill and gastropoda decreased as the concentration of Na-PCP increasing,which showed a significant time-dosage inhibited effect,and the activity of AK in gastropoda decreased more drastically than that of gill at the same time.The results suggested that AK were sensitive to the exposure of Na-PCP and could be used as a biomarker to evaluate the aquatic environment Na-PCP pollution.

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五氯酚钠对梨形环棱螺的毒理效应研究

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