单 位：
内蒙古畜牧科学院动物营养研究所;宁夏大学农学院动物科学系
摘 要：
选用体质量和出生日期相近的12头中国荷斯坦犊牛,随机分为4组,(40±1)d一次性断奶。采用胃肠外营养(Total parenteral nutrition,TPN)颈静脉灌注丙氨酰谷氨酰胺(Ala-Gln)二肽的方式,研究了不同水平Gln对早期断奶犊牛免疫功能的影响。Ala-Gln灌注剂量为Ⅰ组(对照组,不灌注),Ⅱ组(低水平)0.33 g/(kg.d),Ⅲ组(高水平)1.34 g/(kg.d),Ⅳ组(中等水平)0.68 g/(kg.d),连续灌注7 d。结果表明:补充中等水平的Ala-Gln,可以有效地增加外周血CD2+和CD4+淋巴细胞的含量,使CD4+/CD8+比值增高,同时使血清IgA和IgG含量和空肠和回肠粘液S-IgA含量显著升高,从而增强了机体的免疫功能。
译 名：
Effects of different injected glutamine levels on immune function in early-weaned calves
作 者：
ZHOU Yu-xiang1,ZHANG Pei-song1,LU De-xun2*,SUN Hai-zhou2(1.Department of Animal Science of Agricultural College,Ningxia University,Yinchuan 750021,China;2.Institute of Animal Nutrition,Inner Mongolian Academy of Agricultural Animal Science,Huhhot 010030,China)
关键词：
early-weaned calves;Ala-Gln;immune function
摘 要：
Twelve Chinese Holstein calves with similar weight and date of birth were selected and divided randomly into four groups.They were weaned at(40±1) d.Alanyl-glutamine peptide(Ala-Gln) was supplemented through jugular vein by total parenteral nutrition(TPN) to explore the effects of different injected glutamine levels on immune function in early-weaned calves.Ala-Gln levels were designed as follows:trial Ⅰ(control group,0 g/(kg·d),trail Ⅱ(low-Gln group,0.33 g/(kg·d),trail Ⅲ(high-Gln group,1.34 g/(kg·d),trail Ⅳ(mid-Gln group,0.68 g/(kg·d),and the injection lasted for 7 d continuously.The results indicated that mid-Gln level could increase effectively peripheral blood′s level of CD2+ and CD4+ lymphocyte and the ratio of CD4+/CD8+.At the same time,the levels of serum IgA,IgG and S-IgA in jejunum and ileum mucus increased significantly resulting in improvement of animals'immune function.
