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当前位置: 首页 > 文章 > 非ST段抬高型心肌梗死患者血清胆红素水平与TIMI危险评分的相关性及临床意义 河北北方学院学报(自然科学版) 2016,32 (2) 16-18+22
Position: Home > Articles > Correlation and Clinical Significance of Serum Bilirubin Level and TIMI Risk Score in Patients with Non-ST Segment Elevation Myocardial Infarction Journal of Hebei North University(Natural Science Edition) 2016,32 (2) 16-18+22

非ST段抬高型心肌梗死患者血清胆红素水平与TIMI危险评分的相关性及临床意义

作  者：
王涛
单  位：
山西省大同市第四人民医院心内科
关键词：
胆红素;心肌梗死;TIMI风险评分
摘  要：
目的探讨非ST段抬高型心肌梗死(NSTEMI)患者血清胆红素(BIL)水平与TIMI评分的相关性及临床意义。方法收集104例NSTEMI患者一般资料,包括年龄、性别、体质量指数、血压、糖尿病、低密度脂蛋白胆固醇水平以及吸烟等,清晨空腹采血测定血清总胆红素(TBIL)、直接胆红素(DBIL)、间接胆红素(IBIL)水平。采用TIMI评分标准对NSTEMI患者进行风险评估,计算NSTEMI组患者TIMI评分并进行危险分层,以评分差异分组,分为低位组、中危组、高危组;分析NSTEMI患者血清BIL水平与TIMI积分的相关性及临床意义。结果高危组患者TBIL、IBIL水平明显低于中危组、低危组(P<0.01);NSTEMI组TBIL、IBIL水平与其TIMI分值均有负相关关系(r=-0.20,P<0.05;r=-0.228,P<0.05)。结论NSTEMI患者血清BIL水平与TIMI积分呈负相关,TBIL对NSTEMI患者早期危险度分层具有预测价值。
译  名：
Correlation and Clinical Significance of Serum Bilirubin Level and TIMI Risk Score in Patients with Non-ST Segment Elevation Myocardial Infarction
作  者：
WANG Tao;Department of Cardiology,the Fourth People's Hospital of Datong;
关键词：
bilirubin;;myocardial infarction;;TIMI risk score
摘  要：
Objective To investigate the correlation and clinical significance of serum bilirubin(BIL)level and TIMI score in patients with non-ST segment elevation myocardial infarction(NSTEMI).MethodsThe clinical data of 104 patients with NSTEMI patients were collected,including age,gender,body mass index,blood pressure,diabetes,low-density lipoprotein cholesterol(LDL-C)levels and smoking,and the morning fasting blood determination of serum total bilirubin(TBIL),direct bilirubin(DBIL)and indirect bilirubin(IBIL).The TIMI risk score was used for risk assessment of patients with NSTEMI.TIMI scores of NSTEMI patients were calculated and their risks were stratified.Based on score differences,the patients were divided into low-risk group,middle-risk group and high-risk group.The correlation of serum bilirubin levels and TIMI risk score was analyzed as well as its clinical significance.Results 1.TIMI risk stratification showed that the levels of serum total bilirubin(TBIL)and indirect bilirubin(IBIL)in high-risk group were significantly lower than those in middle-risk group and low-risk group(P<0.01).2.The levels of TBIL and IBIL in the NSTEMI group were negatively correlated with their TIMI scores(r=-0.20,P<0.05 vs.r=-0.228,P<0.05).Conclusion The level of serum BIL in NSTEMI patients is negatively correlated with TIMI score,and measurement of TBIL has predictive value for early risk stratification in NSTEMI patients.

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