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Position: Home > Articles > Genetic Polymorphisms in Exon 4 of IGF2 Gene of Red Cattle and Its Genetic Effects Journal of Jilin Agricultural University 2011,33 (3) 324-326+331

草原红牛IGF2基因外显子4的遗传多态性及遗传效应分析

作  者:
牛伟萍;刘晶;张金玉;张明军;杨润军;赵志辉
单  位:
吉林大学畜牧兽医学院
关键词:
草原红牛;胰岛素样生长因子2;遗传多样性;遗传效应
摘  要:
运用PCR-SSCP方法检测草原红牛IGF2基因第4外显子的多态性,采用最小二乘法拟合线性模型将突变位点的不同基因型与牛胴体和肉质性状进行关联分析。结果表明:在外显子4上有1个SNP位点(C250G),该基因具有AA和AB 2种基因型,草原红牛AB基因型个体肋脂质量比AA基因型个体高3.1%(P<0.05),骨质量和眼肌面积较AA基因型个体分别低15.7%和46.05%(P<0.01)。IGF2基因的遗传多态性可能直接影响草原红牛的肉质性状。
译  名:
Genetic Polymorphisms in Exon 4 of IGF2 Gene of Red Cattle and Its Genetic Effects
作  者:
NIU Wei-ping,LIU Jing,ZHANG Jin-yu,ZHANG Ming-jun,YANG Run-jun,ZHAO Zhi-hui College of Veterinary Medicine,Jilin University,Changchun 130062,China
关键词:
Red Cattle;IGF2 gene;genetic polymorphism;genetic effect
摘  要:
The method of PCR-SSCP was used to study the genetic polymorphism of IGF2 gene exon 4 in Red Cattle.Using the linear model,the correlations of different genotypes of mutation points with the naked body and meat quality traits was analyzed.The results showed that there is a SNP site(C250G) in exon 4.The gene has two genotypes,AA and AB.In rid fat weight,genotype AB is 3.1% higher than genotype AA(P<0.05).Meanwhile,in bone weight and eye muscle area,genotype AB is 15.7% and 46.05% lower than genotype AA,respectively(P<0.01). The genetic polymorphism of the IGF2 gene Exon4 probably has direct genetic effects on meat quality traits in Red Cattle.

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