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Hubei Agricultural Sciences
2009,48
(3)
109-111
井冈霉素高产菌株的复合诱变筛选
作 者：
张茜茜;朱永强;刘华梅;丁咏梅;李世杰
单 位：
武汉科诺生物科技股份有限公司;湖北工业大学/湖北省工业微生物重点实验室
关键词：
吸水链霉菌井冈变种;诱变;井冈霉素A
摘 要：
吸水链霉菌井冈变种(Streptomyces hygroscopicus var.jinggangensis Yen)KN-16经紫外线、60Coγ射线、亚硝酸-紫外线复合诱变处理,摇瓶发酵筛选得到一株井冈霉素A高产菌株F-101,该菌株产井冈霉素A含量较出发菌株提高了33.5%。
译 名：
Screening on High-yield Jinggangmycin Strain by Combining Mutation
作 者：
ZHANG Qian-qian1,ZHU Yong-qiang1,LIU Hua-mei2,DING Yong-mei2,LI Shi-jie1 (1.Hubei University of Technology / Hubei Industrial Microbiology Key Laboratory, Wuhan 430068, China; 2.Wuhan Kernel Bio-tech Co., Ltd. Wuhan 430074, China)
关键词：
Streptomyces hygroscopicus var. jinggangensis Yen; mutation; Jinggangmycin A
摘 要：
Jinggangmycins A strain KN-16 of Streptomyces hygroscopicus var. jinggangensis Yen was treated by UV,60Coγ Radial and UV with HNO2 respectively, a high-yield Jinggangmycins A strain F-101 was obtained, the Jinggangmycin A yield was 33.5% higher than that by the original strain on shaking flask fermentation.
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