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Position: Home > Articles > Synthesis and Biological Activities of Pyraclostrobin Agrochemicals 2013,52 (6) 408-410

吡唑醚菌酯的合成和初步生物活性

作  者:
马海军;曹庆亮;马亚芳;倪珏萍
单  位:
江苏省农药研究所股份有限公司江苏南方农药研究中心
关键词:
吡唑醚菌酯;合成;邻硝基甲苯;对氯苯胺;生物活性
摘  要:
[方法]吡唑醚菌酯属甲氧基丙烯酸酯类杀菌剂,具有优良的生物活性,以邻硝基甲苯和对氯苯胺为起始原料,经重氮化、环合、氧化、溴化、缩合、还原、酰化、甲基化等工艺制备吡唑醚菌酯。[结论]以对氯苯胺计总收率大于55%,产品纯度大于95%。该工艺具有生产成本低、操作简便和易于工业化生产等特点。吡唑醚菌酯对小麦赤霉病和水稻纹枯病具有优良离体活性。
译  名:
Synthesis and Biological Activities of Pyraclostrobin
作  者:
MA Hai-jun,CAO Qing-liang,MA Ya-fang,NI Jue-ping(Jiangsu Pesticide Research Institute Co.,Ltd.,Jiangsu Southern Pesticide Research Center,Nanjing 210046,China)
关键词:
pyraclostrobin;synthesis;o-nitrotoluene;p-chloroaniline;biological activities
摘  要:
[Methods] Pyraclostrobin is a strobilurin fungicide with excellent biological activties.A preparation method of pyraclostrobin was described by using o-nitrotoluene and p-chloroaniline as raw materials including diazotization,cyclization,oxidation,bromination,condensation,reduction,acetylation and methylation.[Conclusions] The total yield was more than 55% based on p-chloroaniline,and the purity was higher than 95%.This process was easy to be industrialized with lower cost.Pyraclostrobin have a good fungicidal activity in vitro against wheat scab(Gibberella zeae) and rice sheath blight disease(Rhizoctonia solani).

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