Kan Wu;Huayu;Qiao Qiao;Mu;Qing Li;Lianghua;Youguang Guo;Wanzheng;Peng Peng;Xianwen;Dong Sun;Hua Hua;Biao Huang;Jing-shu;Mei Mei;Shuq

irgc gene;porcine;90;cattle;dog;huma

[Objective] This study was to analyze porcine IRGC gene, so as to lay the foundation of further revealing its function. [Method] IRGC gene was cloned by using EST information together with sequencing, then aligned with the IRGC sequences of human, cattle, dog and orangutan for obtaining their similarities. [Result] Porcine IRGC cDNA obtained in the present study was 1 558 bp in length(GenBank accession number EU703776), which shared high similarity with human (86%), cattle (90%), dog (91%), orangutan (84%). Sequence analysis shows that porcine IRGC gene encodes 464 amino acid residues which share high homologies with the counterparts from human(90%), cattle (93%), dog (95%), orangutan (90%). [Conclusion] Cloning and sequence analysis of porcine IRGC gene would be helpful for studying its functions.