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Position: Home > Articles > Research progress in anti-diabetic actions of pomegranate(Punica granatum L. ) Science and Technology of Food Industry 2012,33 (23) 370-373

石榴抗糖尿病生物活性的研究进展

作  者:
刘慧;赵文恩;康保珊
单  位:
中国农业科学院郑州果树研究所
关键词:
石榴;抗糖尿病;活性成分;作用机制
摘  要:
体外和体内实验均证实石榴汁、石榴皮、石榴花、石榴籽和石榴叶等具有抗糖尿病的功效,综述了石榴多个部位的降血糖效果、降血糖活性成分及其作用机制的研究进展。石榴中的多酚类是抗糖尿病的主要活性物质,主要通过提高胰岛素受体敏感性、增强PPAR-γ(Peroxisome proliferator-activated receptor,过氧化酶体增殖物激活受体)的表达、抑制α-葡萄糖苷酶活性等作用达到抗糖尿病的功效,为石榴的进一步开发利用提供参考。
译  名:
Research progress in anti-diabetic actions of pomegranate(Punica granatum L. )
作  者:
LIU Hui,ZHAO Wen-en*,KANG Bao-shan (Zhengzhou Fruit Research Institute of CAAS,Zhengzhou 450009,China)
关键词:
pomegranate(Punica granatum L. );anti-diabetes;active compounds;mechanism of action
摘  要:
There are anti-diabetic constituents in several parts of pomegranate including juice,peels,flowers,seeds,and leaves in vivo or vitro research. The anti-diabetic activities,major active compounds and mechanisms of different parts in pomegranate were summarized in this paper. Polyphenols were the major active components for anti-diabetic activity. The sensitivity of insulin receptor and the expression of peroxisome proliferator-activated receptor were improved as well as the activity of α-glucosidase was inhibited,which were major reasons for hypoglycemic activity of pomegranate. The results provide a powerful support for further development of pomegranate utilization.

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