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Position: Home > Articles > Study on Effects of Ranunculus ternatus against Mycobacterium Tuberculosis in vitro Journal of Anhui Agricultural Sciences 2015 (19) 76-77+94

猫爪草体外抗结核作用研究

作  者:
杨堃;邓可众;李汉兴;熊英
单  位:
重庆市食品药品检验所;江西中医药大学药学院
关键词:
猫爪草;H37RV;耐药结核
摘  要:
[目的]观察3种猫爪草的醇提物及猫爪草各不同极性部位对标准结核菌株和耐药菌株的体外抑菌效果。[方法]采用绝对浓度法,进行3种猫爪草70%乙醇提取物和猫爪草醇提物经萃取分离得到的4个极性不同部位对结核分支杆菌(H37RV)和耐药菌株的药物敏感试验。[结果]3种猫爪草(4 mg/ml)对标准菌株和耐药菌株均有抑菌作用,且石油醚萃取部位抑菌浓度最低为2 mg/ml。[结论]猫爪草具有明显的体外抗耐药结核作用,以石油醚萃取部位抑菌效果最佳。
译  名:
Study on Effects of Ranunculus ternatus against Mycobacterium Tuberculosis in vitro
作  者:
YANG Kun;DENG Ke-zhong;LI Han-xing;XIONG Ying;Chongqing Institute for Food and Drug Control;School of Medicine,Jiangxi University of Traditional Chinese Medicine;
关键词:
Ranunculus ternatus;;H37RV;;Drug-resistant tuberculosis
摘  要:
[Objective] To observe the inhibiting effects of alcohol extraction of three kinds and different polar parts of Ranunculus ternatus on drug-resistant tuberculosis in vitro. [Method] The absolute concentration method was used for susceptibility test on tuberculosis bacteria H37 RV and drug-resistant tuberculosis strains with different alcohol extraction of three kinds and different polar parts of Ranunculus ternatus. [Result] The growth of Mycobacterium tuberculosis and drug-resistant tuberculosis could be inhibited by three kinds of R. ternatus( 4 mg / ml),MIC of the petroleum ether extract was 2 mg / ml. [Conclusion] R. ternatus had obvious antibacterial activity and the effect of petroleum ether layer was the best.

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