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Position: Home > Articles > Study on Ache Easing and Anti-inflammafory Effect of Cynanchum komanovii Progress in Veterinary Medicine 2006,27 (11) 103-104

牛心朴子生物碱的镇痛抗炎作用试验

作  者:
张永康;何生虎;李勇
单  位:
宁夏大学农学院动科系
关键词:
牛心朴子;生物碱;镇痛作用;抗炎作用
摘  要:
用热板法研究不同浓度的牛心朴子总碱对小鼠的镇痛作用,结果表明,50 mg/kg体重的总碱对热板法所致小鼠的疼痛反应具有明显的抑制作用;以小鼠为实验动物,选用不同浓度的牛心朴子生物碱注射剂对其抗炎作用进行了研究。结果表明,牛心朴子生物碱的最小浓度在1.0 mg/mL时,对二甲苯致小鼠的耳壳肿胀有明显的抑制作用,作用与浓度呈正相关。
译  名:
Study on Ache Easing and Anti-inflammafory Effect of Cynanchum komanovii
作  者:
ZHANG Yong-kang,HE Sheng-hu,LI Yong (Department of Animal Science,Agricultrue Academy,Ningxia University,Yinchuan,Ningxia,750021,China)
关键词:
Cynanchum komanovii;alkaloid;ache easing;antiinflammafory effect
摘  要:
Studies on easeing ache effect from different concentrations alkaloid of Cynanchum komanovii with hot plate were conducted.The result showed 50 mg/kg weight had clear restraint ache of mice;Choose 0.5 mL different concentrations(0.5,1.0,1.5 mg/mL) alkaloid of Cynanchum komanovii injectables researching anti-inflammafory effect of Cynanchum komanovii.The results showed that the smallest concentration of alkaloid Cynanchum komanovii in 1.0 mg/mL had obvious inhibition effect to ears swelling of mice by xylene C_(6)H_(4)(CH_(3))_(2)(P<0.05),the effect and concentration was positive relevant.

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