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Position: Home > Articles > Relationships between aminopeptidase N—the receptor for Bt toxin in Helicoverpa armigera and Bt resistance Plant Protection 2007,33 (1) 1-5

棉铃虫Bt毒素受体蛋白—氨肽酶N与抗性的关系

作  者:
常洪雷;梁革梅;于宏坤;王桂荣;吴孔明;郭予元
单  位:
中国农业科学院植物保护研究所植物病虫害生物学国家重点实验室
关键词:
棉铃虫;Bt;氨肽酶N;抗性
摘  要:
随着我国转基因棉花种植面积的日益增加,主要目标害虫—棉铃虫的抗性问题越来越被大家所关注。氨肽酶N(aminopeptidase N,APN)是一类昆虫中肠内Bt毒素的受体蛋白,其结构、结合位点的改变或基因突变可能是昆虫对Bt毒素产生抗性的重要原因。本文通过分析Bt毒素的作用方式,从生化、生理、分子生物学等方面探讨了棉铃虫Bt毒素受体蛋白APN与抗性的关系。
译  名:
Relationships between aminopeptidase N—the receptor for Bt toxin in Helicoverpa armigera and Bt resistance
作  者:
Chang Honglei,Liang Gemei,Yu Hongkun,Wang Guirong,Wu Kongming,Guo Yuyuan(State Key Laboratory of Plant Disease and Insect Pests,Institute of Plant Protection,Chinese Academy of Agricultural Sciences,Beijing 100094, China)
关键词:
Helicoverpa armigera;Bacillus thuringiensis;aminopeptidase N;resistance
摘  要:
As the planting area of Bt cotton rapidly increases in China,more and more attention has been paid to possible development of resistance to Bt in cotton bollworm,Helicoverpa armigera,the most important pest of cotton.Aminopeptidase N(APN) is one kind of receptors for Bacillus thuringiensis(Bt) toxin in insect midguts.The change in its structure,binding sites and gene mutation may be the main mechanisms in relation to Bt resistance.The relationships between APN and resistance of cotton bollworm to Bt were discussed in terms of its biochemistry,physiology and molecular biology by analyzing the action modes of Bt toxin.

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