中国农业科学院农业信息研究所 中国农学会
Agricultural Information Institute of CAAS China Association of Agricultural Science Societies
En
Ch
中国农业科学院农业信息研究所 中国农学会 主办

AI检索

订阅

返回顶部
当前位置: 首页 > 文章 > 外泌体作为温郁金活性成分姜黄素载体的研究进展 园艺与种苗 2020 (2) 40-44
Position: Home > Articles > Research Progress of the Exosomes as Drug Delivery Vehicles of Curcumin of Active Ingredient in Curcuma wenyujin Horticulture & Seed 2020 (2) 40-44

外泌体作为温郁金活性成分姜黄素载体的研究进展

作  者：
郭月琴;赵祺;袁玮;姜程曦
单  位：
温州大学生命科学研究院;大理药业股份有限公司;浙江省生物医药协同创新中心
关键词：
外泌体;姜黄素;温郁金;载体
摘  要：
外泌体是细胞分泌的纳米级别膜性小泡,能够介导细胞间信号转导和信息交流,并且参与人体内各种疾病的生理过程,可以作为一种天然的药物载体。姜黄素是中药温郁金的活性成分之一,因其广泛而明确的药理作用成为现代药理研究的热点,但由于姜黄素溶解度差、结构不稳定、体内代谢过程快,生物利用度低,严重限制了其临床推广应用。而通过将外泌体作为姜黄素载体,可以更好地发挥药理作用。该研究综述了外泌体生物学特性及外泌体作为姜黄素载体的研究进展。
译  名：
Research Progress of the Exosomes as Drug Delivery Vehicles of Curcumin of Active Ingredient in Curcuma wenyujin
作  者：
GUO Yue-qin;Institute of Life Sciences,Wenzhou University;
关键词：
Exocrine;;Curcumin;;Curcuma wenyujin;;Carrier
摘  要：
Exocrine is a nanoscale membranous vesicle secreted by cells. It can mediate signal transduction and information exchange between cells,and participate in the physiological processes of various diseases in the human body. It can be used as a natural drug carrier. Curcumin is one of the active ingredients of tulip in traditional Chinese medicine. Because of its extensive and clear pharmacological action,curcumin has become a hot spot in modern pharmacological research. However,due to the poor solubility,structural instability,rapid metabolic process in the body and low bioavailability of curcumin,the clinical application of curcumin is seriously restricted. By using exocrine as the carrier of curcumin,it can play a better role in pharmacology. The biological characteristics of exocrine and exocrine body as the carrier of curcumin are studied in this paper.

相似文章

导出引用
计量
文章访问数: 16
HTML全文浏览量: 0
PDF下载量: 0

所属期刊

推荐期刊

友情链接Friendly link
农业信息研究所Agricultural information institute 农业智能知识服务平台Agricultural intelligent knowledge service platform 农业学术服务平台Agricultural Knowledge Service System 中国知网CNKI 维普网VIP 万方WANFANG DATA
联系我们Contact us

电话Tell：010-82109652-808

邮箱E-mail：agrijournal@caas.cn

服务Service
关于我们About us 意见建议Opinions and suggest
版权说明Copyright
单位：中国农业科学院农业信息研究所 中国农学会 © 2017中国农业科学院农业信息研究所 ICP备案号：京ICP备09089781号-46