当前位置: 首页 > 文章 > 致病性大肠埃希菌常见毒力因子分子生物学特征研究进展 吉林农业大学学报 2014,36 (4) 379-383+394
Position: Home > Articles > Advances on Molecular Biological Characters of Virulent Factors from Pathogenic Escherichia coli Journal of Jilin Agricultural University 2014,36 (4) 379-383+394

致病性大肠埃希菌常见毒力因子分子生物学特征研究进展

作  者:
胡桂学;饶桂波;郭慧;王开;邵洪泽;陈中秋;张迪
单  位:
辽宁成大生物股份有限公司;吉林农业大学动物科学技术学院;广西兽医研究所;吉林省畜牧兽医科学研究院
关键词:
大肠埃希菌;毒力因子;分子生物学
摘  要:
大肠埃希菌常见的毒力因子包括肠毒素、黏附素性菌毛、类志贺菌毒素及毒力岛等,这些毒力因子决定了大肠埃希菌的致病性。研究毒力因子能够了解大肠杆菌的致病机制,进而根据该菌的致病机制开发免疫制剂和靶向药物。为了阐明大肠杆菌的致病机制,更好地防控该病,文中对该菌的肠毒素、黏附素性菌毛、类志贺菌毒素及毒力岛等的分子生物学研究进展进行了综述。
译  名:
Advances on Molecular Biological Characters of Virulent Factors from Pathogenic Escherichia coli
作  者:
HU Gui-xue;RAO Gui-bo;GUO Hui;WANG Kai;SHAO Hong-ze;CHEN Zhong-qiu;ZHANG Di;College of Animal Science and Technology,Jilin Agricultural University;Guangxi Veterinary Research Institute;Academy of Animal Science and Veterinary Medicine of Jilin Province;Liaoning Chengda Biotechnoloy Co. Ltd.;
关键词:
Escherichia coli;;virulent factor;;molecular biology
摘  要:
Common virulent factors of Escherichia coli include enterotoxin,adhesion pili,Shiga toxin and pathogenicity island,etc. These factors determine the virulence of pathogenic E. coli. To study virulent factors can help the understanding of the pathogenesis of E. coli,and then develop preventive products and aimed drugs based on the characters of pathogenic bacteria. For declaring the pathogenesis of the pathogen to prevent and the control the disease,enterotoxin,adhesion pili,Shiga toxin and pathogenicity islands were reviewed in the paper.

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