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Study on the chemical constituents of chlorogenic acids from the dried leaves of Lonicera similis Hemsl.

作  者:
Weng Yu-xin;Xianghong Chen;Liu ZhanHou;Wei QuanJi
单  位:
Medical College, Qinghai University, Xining, Qinghai 810001, Chin;Medical College, Qinghai University, Xining, Qinghai 810001, China
关键词:
lonicera similis hemsl.;chlorogenic acid;dried leaves;chlorogenic acids;caffeoyl;isolate
摘  要:
[Objective] To study the chemical constituents in the dried leaves of Lonicera similis Hemsl., so as to provide guidance for its further utilization and finding out new active substance. [Method] Chlorogenic acids were isolated and purified by solvent extraction and column chromatographic methods, and then identified by various spectroscopic methods. [Result] Six compounds were isolated from the dried leaves of Lonicera similis Hemsl., including chlorogenic acid (I), chlorogenic acid methyl ester (II), chlorogenic acid ethyl ester (III), 5-caffeoyl-1, 3-quinide (IV), methyl 3, 4-di-O-caffeoyl quinate (V) and methyl 3, 5-di-O-caffeoyl quinate (VI). [Conclusion] Apart from the chlorogenic acids, other compounds were extracted from this plant for the first time.
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