当前位置: 首页 > 文章 > 日粮中添加天蚕素抗菌肽对断奶仔猪生产性能、免疫性能及血清生化指标的影响 中国畜牧兽医 2014,41 (7) 99-103
Position: Home > Articles > Effects of Antibacterial Peptide Cecropin on Prouduction Performance,Immune Function and Serum Biological Parameters of Weaner Piglets China Animal Husbandry & Veterinary Medicine 2014,41 (7) 99-103

日粮中添加天蚕素抗菌肽对断奶仔猪生产性能、免疫性能及血清生化指标的影响

作  者:
李波;韩文瑜
单  位:
吉林大学动物医学院
关键词:
天蚕素抗菌肽;断奶仔猪;生产性能;免疫性能;血清生化指标
摘  要:
本试验旨在研究日粮中添加天蚕素抗菌肽对断奶仔猪生产性能、免疫性能及血清生化指标的影响。选用平均体重为(8.35±0.12)kg的杜×大×长三元杂交猪240头,采用单因子完全随机试验设计,分为4组,即对照组:基础日粮(玉米—豆粕型);抗生素组:基础日粮+140mg/kg吉他霉素(50%)+100mg/kg喹乙醇+600mg/kg硫酸抗敌素(10%);抗菌肽组:基础日粮+350mg/kg天蚕素抗菌肽;配伍组:基础日粮+250mg/kg天蚕素抗菌肽+50mg/kg喹乙醇+200mg/kg硫酸抗敌素(10%),每组6个重复,每个重复10头猪(公、母各半)。预试期7d,正试期34d。结果表明,与对照组相比,配伍组显著提高断奶仔猪平均日增重(P<0.05),抗生素组与抗菌肽组显著降低断奶仔猪平均日采食量(P<0.05),各试验组均可显著降低断奶仔猪料重比和腹泻率(P<0.05);抗菌肽组与配伍组可显著提高平均抗体阻断率及血清中IgG、IgA含量(P<0.05);抗菌肽组与配伍组可显著降低血清尿素氮和血糖含量(P<0.05),但可显著提高血清中总蛋白、白蛋白含量(P<0.05)。由此得出,在断奶仔猪日粮中添加适宜水平天蚕素抗菌肽可部分替代饲用抗生素,高剂量添加时可完全取代饲用抗生素。
译  名:
Effects of Antibacterial Peptide Cecropin on Prouduction Performance,Immune Function and Serum Biological Parameters of Weaner Piglets
作  者:
LI Bo;HAN Wen-yu;College of Veterinary Medicine,Jilin University;Beijing Sinagri Yinthai Biotechnology Co.,Ltd.;Sinagri Yinthai Linzhou Biological Keyuan Co.,Ltd.;
关键词:
antimicrobial peptide cecropin;;weaner piglets;;production performance;;immune function;;serum biological parameters
摘  要:
This experiment was conducted to study the effects of antimicrobial peptide cecropin on production performance,immune function and serum biological parameters of weaner piglets.A total of 240 weaner hybrid piglets(Landrace×Large White×Duroc)with average body weight(8.35±0.12)kg were randomly divided into 4treatments with 6replicates of 10 each.The four treatments were control group(fed a basal diet),antibiotics group(fed basal diet+140mg/kg 50%kitasamycin+100mg/kg olaquindox+600mg/kg 10%colistin sulfate),antimicrobial peptide group(fed basal diet+350mg/kg antimicrobial peptide cecropin),compatibility group(antibiotics+antibacterial peptide group)(fed basal diet+250mg/kg antimicrobial peptide cecropin+50mg/kg olaquindox+200mg/kg 10%colistin sulfate),each group was half male and half female.The pre-test period lasted for 7days,the trial period lasted for 34 days.The results showed that compared with control group,the average daily gain in compatibility group was significantly increased(P<0.05),the average daily feed intake in antibiotic group and antimicrobial peptide group was significantly decreased(P<0.05),the feed conversion ratio and diarrhea rate in all three experimental groups were significantly decreased(P<0.05).The antibody blocking rate and serum IgG,IgA contents in antimicrobial peptide group and compatibility group were significantly increased(P<0.05),the serum urea nitrogen and blood sugar contents in antimicrobial peptide group and compatibility group were significantly decreased(P<0.05),but the serum total protein and albumin contents were significantly increased(P<0.05).In conclusion,dietary supplementation appropriate level of antimicrobial peptide cecropin could replace part of the antibiotics,and adding high dose of antimicrobial peptide cecropin could replace antibiotics used in feed completely.

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